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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >Tolnaftate

Tolnaftate

Tolnaftate Structure
  • ₹3900 - ₹21812.38
  • Product name: Tolnaftate
  • CAS: 2398-96-1
  • MF: C19H17NOS
  • MW: 307.41
  • EINECS:219-266-6
  • MDL Number:MFCD00056611
  • Synonyms:2-naphthyl n-methyl-n-(3-tolyl)thionocarbamate;METHYL 3-TOLYLTHIOCARBAMIC ACID O-NAPHTHALEN-2-YL ESTER;METHYL-[3-METHYLPHENYL]-CARBAMOTHIOIC ACID O-2-NAPHTHYL ESTER;Aftate;Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester;Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester;Carbanilic acid, N,m-dimethylthio-, O-2-naphthyl ester;Chinofungin
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1778
  • Product descriptionTolnaftate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹21812.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6638
  • Product descriptionTolnaftate
  • Packaging5G
  • Price₹17255.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6638
  • Product descriptionTolnaftate
  • Packaging1G
  • Price₹6419.23
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3059
  • Product descriptionTolnaftate
  • Packaging5G
  • Price₹9000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3059
  • Product descriptionTolnaftate
  • Packaging1G
  • Price₹3900
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1778 Tolnaftate Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹21812.38 2022-06-14 Buy
Sigma-Aldrich(India) T6638 Tolnaftate 5G ₹17255.05 2022-06-14 Buy
Sigma-Aldrich(India) T6638 Tolnaftate 1G ₹6419.23 2022-06-14 Buy
TCI Chemicals (India) T3059 Tolnaftate 5G ₹9000 2022-05-26 Buy
TCI Chemicals (India) T3059 Tolnaftate 1G ₹3900 2022-05-26 Buy

Properties

Melting point :110.5-111.5°C
Boiling point :453.4±38.0 °C(Predicted)
Density :1.1328 (rough estimate)
refractive index :1.6970 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
form :powder
pka :-0.35±0.50(Predicted)
color :white to off-white
Water Solubility :<0.1 g/100 mL at 22 ºC
λmax :258nm(MeOH)(lit.)
Merck :14,9519
InChIKey :FUSNMLFNXJSCDI-UHFFFAOYSA-N
LogP :5.142 (est)
NIST Chemistry Reference :Tolnaftate(2398-96-1)
EPA Substance Registry System :Tolnaftate (2398-96-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete?s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.

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Suppliers and manufacturers

GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED Unilab Company CNS CHEMICALS Souvin Pharmaceuticals Pvt Ltd Shimoga Chemicals Aarti Drugs Ltd (part of Aarti Group of Industries) Omshri Labs Pvt Ltd Medilink Pharmachem OCEAN TRADING CORPORATION Festiva Pharma