Verteporfin
- ₹12297.2 - ₹50076.45
- Product name: Verteporfin
- CAS: 129497-78-5
- MF: 2C41H42N4O8
- MW: 1437.61
- EINECS:
- MDL Number:MFCD11982858
- Synonyms:Verteporfin(DB00460);Verteprofin;Verteporfin;Verteporphin;24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, (4R,4aS)-rel-;VERTEPIRFIN;9-methyl (I)13-methyl (II)trans-(±)- 18-ethenyl- 4,4a-dihydro-3,4 -bis(methoxycarbonyl)- 4a,8,14,19-tetramethyl- 23H,25H-benzo[b]porphine- 9,13- dipropanoate;(4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0534
- Product descriptionVerteporfin ≥94% (HPLC)
- Packaging5MG
- Price₹12297.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0534
- Product descriptionVerteporfin ≥94% (HPLC)
- Packaging25MG
- Price₹50076.45
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0534 | Verteporfin ≥94% (HPLC) | 5MG | ₹12297.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0534 | Verteporfin ≥94% (HPLC) | 25MG | ₹50076.45 | 2022-06-14 | Buy |
Properties
storage temp. :-20°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :Black
Stability :Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YHNBVDZVUQFVLS-RDSGBMLISA-N
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :Black
Stability :Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YHNBVDZVUQFVLS-RDSGBMLISA-N
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. It accumulates in these abnormal blood vessels and, when activated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces a highly reactive short-lived singlet oxygen and other reactive oxygen radicals, generating local damage to the endothelium and vessel occlusion. Verteporfin can also inhibit autophagosome formation by directly targeting and modifying p62, a scaffold and adaptor protein that binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes.More related product prices
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