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Vorapaxar Sulfate

Vorapaxar Sulfate Structure
  • ₹0
  • Product name: Vorapaxar Sulfate
  • CAS: 705260-08-8
  • MF: C29H35FN2O8S
  • MW: 590.66
  • EINECS:
  • MDL Number:MFCD16038877
  • Synonyms:Vorapaxar Sulfate;N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-Fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-Methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbaMic Acid Ethyl Ester Sulfate;Sch 530348;SCH 530348 (H2SO4 Salt);vorapaxar impurity A;Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, sulfate (1:1);SCH-530348;SCH530348;Vorapaxar Sulfate (SCH 530348)
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :4°C, away from moisture
solubility :DMSO : 125 mg/mL (211.63 mM; Need ultrasonic)| (insoluble)
form :Solid
color :White to off-white
Water Solubility :Water : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Merck Sharp & Dohme successfully obtained approval in the EU in 2014 for vorapaxar sulfate, marketed as Zontivity®. The drug is a first-in-class thrombin receptor (also referred to as a protease-activated or PAR-1) antagonist which, when used in conjunction with antiplatelet therapy, has been shown to reduce the chance of myocardial infarction and stroke, particularly in patients with a history of cardiac events. Antagonism of PAR-1 allows for thrombin-mediated fibrin deposition while blocking thrombinmediated platelet activation.

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Suppliers and manufacturers

career henan chemical co
Vorapaxar Sulfate
₹1.00 /1KG
Vorapaxar Sulfate CAS:705260-08-8
CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Beijing Ribio Biotech Co.,Ltd
Chongqing Chemdad Co., Ltd
Shanghai Rochi Pharmaceutical Co.,Ltd.