WEDELOLACTONE
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- ₹4400 - ₹16259.15
- Product name: WEDELOLACTONE
- CAS: 524-12-9
- MF: C16H10O7
- MW: 314.25
- EINECS:200-158-5
- MDL Number:MFCD07778564
- Synonyms:1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one;6H-Benzofuro(3,2-C)(1)benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-;5,11,12-Trihydroxy-7-MethoxycouMestan;1,8,9-trihydroxy-3-Methoxy-6H-benzofuro[3,2-c]chroMen-6-one;IKK Inhibitor II, Wedelolactone ;Wedelia lactone;Wedelolactone;Wedelolactone, ≥98%(HPLC)
3 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 10MG
- ManufacturerTCI Chemicals (India)
- Product numberW0015
- Product descriptionWedelolactone
- Packaging1MG
- Price₹4400
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberW0015
- Product descriptionWedelolactone
- Packaging10MG
- Price₹10600
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberW4016
- Product descriptionWedelolactone ≥98% (HPLC), powder
- Packaging1MG
- Price₹16259.15
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | W0015 | Wedelolactone | 1MG | ₹4400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | W0015 | Wedelolactone | 10MG | ₹10600 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | W4016 | Wedelolactone ≥98% (HPLC), powder | 1MG | ₹16259.15 | 2022-06-14 | Buy |
Properties
Melting point :327～330℃
Boiling point :498.4±45.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 14 mg/mL, soluble
form :solid
pka :6.90±0.20(Predicted)
color :brown-beige
InChIKey :XQDCKJKKMFWXGB-UHFFFAOYSA-N
Boiling point :498.4±45.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 14 mg/mL, soluble
form :solid
pka :6.90±0.20(Predicted)
color :brown-beige
InChIKey :XQDCKJKKMFWXGB-UHFFFAOYSA-N
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Wedelolactone is a natural coumestan originally isolated from plants used in herbal therapies. It inhibits NF-κB signaling at the level of IKK action, resulting in suppression of NF-κB-mediated gene expression at concentrations of 1-100 μM. Wedelolactone can also inhibit hepatitis C virus NS5B RNA-dependent RNA polymerase in vitro (IC50 = 36 μM), STAT1 dephosphorylation (50 μM), and EZH2-EED interactions (Kd = 2.8 μM). Prolonged incubation of HepG2 liver cells with wedelolactone alters lipid metabolism through increased expression of AMPK, PPARα, lipoprotein lipase, and low-density lipoprotein receptor.More related product prices
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