A 967079
- ₹12795.15 - ₹51700.2
- Product name: A 967079
- CAS: 1170613-55-4
- MF: C12H14FNO
- MW: 207.24
- EINECS:
- MDL Number:MFCD20488058
- Synonyms:A 967079;(1E,3E)-1-(4-Fluorophenyl)-2-Methyl-1-penten-3-one oxiMe;1-Penten-3-one, 1-(4-fluorophenyl)-2-methyl-, oxime, (1E,3E)-;(1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-pentene-3-one oxime;TRP Channel,inhibit,Transient receptor potential channels,A 967079,Inhibitor,A-967079,A967079
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0085
- Product descriptionA-967079 ≥98% (HPLC)
- Packaging5MG
- Price₹12795.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0085
- Product descriptionA-967079 ≥98% (HPLC)
- Packaging25MG
- Price₹51700.2
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0085 | A-967079 ≥98% (HPLC) | 5MG | ₹12795.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0085 | A-967079 ≥98% (HPLC) | 25MG | ₹51700.2 | 2022-06-14 | Buy |
Properties
Boiling point :324.4±34.0 °C(Predicted)
Density :1.03±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥12mg/mL
pka :12.23±0.40(Predicted)
form :powder
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
InChI :InChI=1S/C12H14FNO/c1-3-12(14-15)9(2)8-10-4-6-11(13)7-5-10/h4-8,15H,3H2,1-2H3/b9-8+,14-12+
InChIKey :HKROEBDHHKMNBZ-CHBKHGQFSA-N
SMILES :C(/C1=CC=C(F)C=C1)=C(/C)\C(=N\O)\CC
Density :1.03±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥12mg/mL
pka :12.23±0.40(Predicted)
form :powder
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
InChI :InChI=1S/C12H14FNO/c1-3-12(14-15)9(2)8-10-4-6-11(13)7-5-10/h4-8,15H,3H2,1-2H3/b9-8+,14-12+
InChIKey :HKROEBDHHKMNBZ-CHBKHGQFSA-N
SMILES :C(/C1=CC=C(F)C=C1)=C(/C)\C(=N\O)\CC
Safety Information
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Description
The transient receptor potential ankyrin 1 (TRPA1) ion channel integrates the nociception and transmission of diverse potentially damaging and noxious stimuli, including cold, electrophilic compounds, divalent cations, and mechanical stimulation. A-967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectively. It attenuates cold allodynia following nerve injury without producing locomotor or cardiovascular side effects. A-967079 also suppresses neuronal activity in response to mechanical stimulation and diminishes postoperative pain due to mechanical stimuli.Related product price
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