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ChemicalBook > Product Catalogue >API >Specialty drugs >Dermatology drugs >Acitretin

Acitretin

Acitretin Structure
  • ₹4200 - ₹19809
  • Product name: Acitretin
  • CAS: 55079-83-9
  • MF: C21H26O3
  • MW: 326.43
  • EINECS:259-474-4
  • MDL Number:MFCD00866632
  • Synonyms:Acetretin;9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid;Acitretin (200 mg);Acitretin (200 mg)F0E2660.998mg/mg(ai);Acitreti;Acitretin (EP5.0);Acitretin A;6,8-nonatetraenoicacid,3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-4
Price7 Properties Safety Information Description
7 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 25MG
  • 50MG
  • 100MG
  • 250MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberA3097
  • Product descriptionAcitretin
  • Packaging50MG
  • Price₹4200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA3097
  • Product descriptionAcitretin
  • Packaging250MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number44707
  • Product descriptionAcitretin ≥98.0% (HPLC)
  • Packaging25MG
  • Price₹5693.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1523
  • Product descriptionAcitretin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹13238.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number44707
  • Product descriptionAcitretin ≥98.0% (HPLC)
  • Packaging100MG
  • Price₹14808.6
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number A 1413
  • Product descriptionAcitretin (HPLC) 98%
  • Packaging25mg
  • Price₹5904
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number A 1413
  • Product descriptionAcitretin (HPLC) 98%
  • Packaging100mg
  • Price₹19809
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A3097 Acitretin 50MG ₹4200 2022-05-26 Buy
TCI Chemicals (India) A3097 Acitretin 250MG ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) 44707 Acitretin ≥98.0% (HPLC) 25MG ₹5693.95 2022-06-14 Buy
Sigma-Aldrich(India) PHR1523 Acitretin Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹13238.98 2022-06-14 Buy
Sigma-Aldrich(India) 44707 Acitretin ≥98.0% (HPLC) 100MG ₹14808.6 2022-06-14 Buy
ottokemi A 1413 Acitretin (HPLC) 98% 25mg ₹5904 2022-05-26 Buy
ottokemi A 1413 Acitretin (HPLC) 98% 100mg ₹19809 2022-05-26 Buy

Properties

Melting point :228-230°C
Boiling point :404.46°C (rough estimate)
Density :1.1348 (rough estimate)
refractive index :1.4700 (estimate)
storage temp. :-20°C
solubility :Practically insoluble in water, sparingly soluble in tetrahydrofuran, slightly soluble in acetone and in ethanol (96 per cent), very slightly soluble in cyclohexane.
form :powder
pka :4.72±0.33(Predicted)
color :Light yellow to yellow
λmax :352nm(MeOH)(lit.)
Merck :14,112
Stability :LIGHT SENSITIVE
CAS DataBase Reference :55079-83-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.

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