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ChemicalBook > Product Catalogue >Catalyst and Auxiliary >UV absorbers >Avobenzone

Avobenzone

Avobenzone Structure
  • ₹4300 - ₹18207.65
  • Product name: Avobenzone
  • CAS: 70356-09-1
  • MF: C20H22O3
  • MW: 310.39
  • EINECS:274-581-6
  • MDL Number:MFCD00210252
  • Synonyms:AVOBENZONE;EUSOLEX(R) 9020;4-tert-butyl-4'-methoxy-dibenzoylmethane;4-T-BUTYL-4'-METHOXY-DIBENZOYLMETHANE;1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione;1-(4-TERT-BUTYLPHENYL)-3-(4-METHOXYPHENYL) 1,3-PROPANEDIOL;1-(P-T-BUTYLPHENYL)-3-(P-METHOXYPHENYL)-1,3-PROPANEDIONE;1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-3-propanedione
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 25MG
  • 1G
  • 25G
  • 100G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3382
  • Product descriptionAvobenzone min. 95.0 %
  • Packaging25G
  • Price₹4300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3382
  • Product descriptionAvobenzone min. 95.0 %
  • Packaging100G
  • Price₹8700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number16633
  • Product descriptionAvobenzone analytical standard
  • Packaging25MG
  • Price₹18207.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1073
  • Product descriptionAvobenzone Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8356.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3382 Avobenzone min. 95.0 % 25G ₹4300 2022-05-26 Buy
TCI Chemicals (India) B3382 Avobenzone min. 95.0 % 100G ₹8700 2022-05-26 Buy
Sigma-Aldrich(India) 16633 Avobenzone analytical standard 25MG ₹18207.65 2022-06-14 Buy
Sigma-Aldrich(India) PHR1073 Avobenzone Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8356.9 2022-06-14 Buy

Properties

Melting point :81-84 °C
Boiling point :463.6±35.0 °C(Predicted)
Density :1.079
vapor pressure :0Pa at 25℃
storage temp. :Inert atmosphere,Room Temperature
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form :Solid
pka :9.74±0.13(Predicted)
color :White to Pale Yellow
Water Solubility :27μg/L at 20℃
λmax :356nm(EtOH)(lit.)
Merck :14,888
InChIKey :GTIRDWBOUTYFQO-UHFFFAOYSA-N
LogP :6.1 at 20℃
CAS DataBase Reference :70356-09-1(CAS DataBase Reference)
EPA Substance Registry System :1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)- (70356-09-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Avobenzone is a full-spectrum ultraviolet A (UVA) blocker. It inhibits UVA-induced increases in melanin levels and tyrosinase activity in B16/F10 melanoma cells (IC30s = 21.94 and 24.25 μM, respectively). Avobenzone (30 μM) also inhibits UVA-induced production of reactive oxygen species (ROS) and 8-hydroxy-2''-deoxyguanosine (8-OH-dG; ), as well as inhibits UVA-induced depletion of glutathione (GSH; ), in B16/F10 cells. It increases nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and upregulates the antioxidant response element (ARE) in UVA-irradiated B16/F10 cells when used at at a concentration of 30 μM. Formulations containing avobenzone have been used as a sun protectant in sunscreen products.

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