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Avobenzone

Avobenzone Structure
CAS No.
70356-09-1
Chemical Name:
Avobenzone
Synonyms
PARSOL 1789;Eusolex 9020;Butylmethoxydibenzoylmethane;AVO;Pars;BMDMB;BF2AVB;P-1789;LGB-AVB;Parsol A
CBNumber:
CB5337318
Molecular Formula:
C20H22O3
Molecular Weight:
310.39
MOL File:
70356-09-1.mol
Modify Date:
2024/7/26 15:15:06
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Avobenzone Properties

Melting point 81-84 °C
Boiling point 463.6±35.0 °C(Predicted)
Density 1.079
vapor pressure 0Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
pka 9.74±0.13(Predicted)
color White to Pale Yellow
Water Solubility 27μg/L at 20℃
λmax 356nm(EtOH)(lit.)
Merck 14,888
InChIKey GTIRDWBOUTYFQO-UHFFFAOYSA-N
LogP 6.1 at 20℃
CAS DataBase Reference 70356-09-1(CAS DataBase Reference)
EPA Substance Registry System 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)- (70356-09-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H413
Precautionary statements  P273-P501
Hazard Codes  N
Risk Statements  50/53
Safety Statements  60-61
RIDADR  UN3077 9/PG 3
WGK Germany  2
HS Code  29145000

Avobenzone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1073 Avobenzone Pharmaceutical Secondary Standard; Certified Reference Material 70356-09-1 1G ₹8356.9 2022-06-14 Buy
Sigma-Aldrich(India) 16633 Avobenzone analytical standard 70356-09-1 25MG ₹18207.65 2022-06-14 Buy
TCI Chemicals (India) B3382 Avobenzone min. 95.0 % 70356-09-1 25G ₹4300 2022-05-26 Buy
TCI Chemicals (India) B3382 Avobenzone min. 95.0 % 70356-09-1 100G ₹8700 2022-05-26 Buy
Product number Packaging Price Buy
PHR1073 1G ₹8356.9 Buy
16633 25MG ₹18207.65 Buy
B3382 25G ₹4300 Buy
B3382 100G ₹8700 Buy

Avobenzone Chemical Properties,Uses,Production

Description

Avobenzone is a full-spectrum ultraviolet A (UVA) blocker. It inhibits UVA-induced increases in melanin levels and tyrosinase activity in B16/F10 melanoma cells (IC30s = 21.94 and 24.25 μM, respectively). Avobenzone (30 μM) also inhibits UVA-induced production of reactive oxygen species (ROS) and 8-hydroxy-2''-deoxyguanosine (8-OH-dG; ), as well as inhibits UVA-induced depletion of glutathione (GSH; ), in B16/F10 cells. It increases nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and upregulates the antioxidant response element (ARE) in UVA-irradiated B16/F10 cells when used at at a concentration of 30 μM. Formulations containing avobenzone have been used as a sun protectant in sunscreen products.

Uses

avobenzone (BMDM, butyl methoxydibenzoylmethane) is a sun-A screen chemical that offers broad-range protection against uVA rays. It is associated with some photoinstability, which can be overcome in the overall sunscreen formulation. It is approved for use up to 3 percent in the united States and 5 percent in the european union. Avobenzone is noted to rarely be photosensitizing.

General Description

Avobenzone is an UVA filter. It is used in sunscreen lotions and cosmetic formulations. It has maximum absorption at ca 340–350 nm, decreasing under UV irradiation resulting in loss of the UVA protecting effect. Its photostability is very sensitive as it is stable in polar protic solvent and is photolabile in nonpolar solvents.

Avobenzone Preparation Products And Raw materials

Raw materials

Sodium carbonate Sulfuric acid Sodium amide Methanol Hydrochloric acid
4-tert-Butylbenzoic acid 4'-Methoxyacetophenone 1-Propanone, 3-[4-(1,1-dimethylethyl)phenyl]-3-hydroxy-1-(4-methoxyphenyl)- Benzoic acid, 4-(1,1-dimethylethyl)-, 1,1-dimethylethyl ester Methyl anisate
Methyl 4-tert-butylbenzoate 2-BROMO-1-(4-TERT-BUTYL-PHENYL)-ETHANONE Ethyl 4-methoxybenzoate 4'-tert-Butylacetophenone Anisonitrile
4-tert-Butyltoluene
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Preparation Products

Avobenzone Suppliers

Global( 559)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
N S CHEMICALS AND CONSULTANTS PVT LTD +91-9867708201 +91-9867708201 Maharashtra, India 18 58 Inquiry
PERFECT CHEMICAL +91-9820465461 +91-9820465461 Mumbai, India 391 58 Inquiry
HJ AROCHEM +91-8690768060 +91-9724420086 Ahmedabad, India 171 58 Inquiry
SODIUM METAL PVT LTD +91-9167214046 +91-9167214046 Mumbai, India 31 58 Inquiry
VINEET LABORATORIES LIMITED +91-9642200049 +91-9642200049 Telangana, India 69 58 Inquiry
Vineet Life Sciences Private Limited +91-9642200049 +91-9642200049 Telangana, India 7 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Salicylates and Chemicals Pvt. Ltd. +91-8879630551 +91-8898005838 Maharashtra, India 61 58 Inquiry
Soros Molecules India +91-7738147222 +91-7738147222 Maharashtra, India 24 58 Inquiry
V V L Pharma Pvt Ltd +91-2227450974 +91-9004121662 Maharashtra, India 8 58 Inquiry
Supplier Advantage
N S CHEMICALS AND CONSULTANTS PVT LTD 58
PERFECT CHEMICAL 58
HJ AROCHEM 58
SODIUM METAL PVT LTD 58
VINEET LABORATORIES LIMITED 58
Vineet Life Sciences Private Limited 58
Ralington Pharma 58
Salicylates and Chemicals Pvt. Ltd. 58
Soros Molecules India 58
V V L Pharma Pvt Ltd 58

Related articles

  • Avobenzone in Sunscreens
  • Avobenzone is a dibenzoylmethane derivative and is a chemical substance that is used in sunscreen products.
  • Nov 29，2022

Avobenzone Spectrum

Avobenzone(70356-09-1)MSAvobenzone(70356-09-1)1HNMRAvobenzone(70356-09-1)13CNMRAvobenzone(70356-09-1)IR1Avobenzone(70356-09-1)IR2

70356-09-1(Avobenzone)Related Search:

tert-Butyldimethylsilyl chloride tert-Butyl hydroperoxide Buprofezin Butyl acrylate butyl rubber
Cyhalofop-butyl Monobenzone 2-Butoxyethanol tert-Butyl methyl ether Dibenzoylmethane
PHENYL VALERATE 4-tert-Butylphenol 4-tert-Butylcatechol Phenylhydrazine 2-Methoxyethanol
Methyl 4-tert-butylbenzoate Butyl acetate 4'-TERT-BUTYLPROPIOPHENONE
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AVOBENZONE EUSOLEX(R) 9020 4-tert-butyl-4'-methoxy-dibenzoylmethane 4-T-BUTYL-4'-METHOXY-DIBENZOYLMETHANE 1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione 1-(4-TERT-BUTYLPHENYL)-3-(4-METHOXYPHENYL) 1,3-PROPANEDIOL 1-(P-T-BUTYLPHENYL)-3-(P-METHOXYPHENYL)-1,3-PROPANEDIONE 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-3-propanedione 1-[4-(1,2-Dimethylethyl)phenyl]-3-(4-methoxyphenyl-1,3-propanedione 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)-1,3-propanedione,Avobenzone, Butyl methoxydibenzoylmethane Avobenzone (500 mg) Avobenzone (500 mg)G1E1090.996mg/mg(dr) Escalol 517 CAPITAL SOLEIL 15 (avobenzone Methoxyphenyl)-3-(4-tert-butylphenyl)-1 Avobenzone (Parsol 1789) 1-(4-tert-butylphenyl)-3-(4-Methoxyphenyl)propane-1,3-diol p-tert-Butyl-p-Methoxy dibenzoyl Methane Pars Butyl MethoxydibenzoylMethane/Avobenzone 1- (4-tert-butylphenyl) -3- (4-Methoxyphenyl) propan-1,3-dione Avobenzone SynonyMs 4-tert-Butyl-4'-Methoxy-dibenzoylMethane Parsol 1789 0 Avobenzon ,Parsol 1789 BF2AVB 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)-1,3-propanedione Butyl methoxydibenzoylmethane Solution, 100ppm 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)propane-1,3-dione 1-(4-Methoxyphenyl)-3-(4-Tert-Butylphenyl)Propan-1,3-Dione EUSOLEX 9020 95- 105% 1-(4-TERT-BUTYLPHENYL)-3-(4-METHOXYPHENYL)-PROPANE-1,3-DIONE [AVOBENZONE] Avobenzone(USP) Butyl-methoxydibenzoylmethane (B-MDM). Sunblock, Parsol1789 1-(4-TERT-BUTYLPHENYL)-3-(4-METHOXYPHENYL)-1,3-PROPANDIONE 4-TERT-BUTYLMETHOXYDIBENZOYLMETHANE TERT-BUTYLMETHOXYDIBENZOYLMETHANE AVOBENZONE / BUTYLMETHOXYDIBENZOYLMETHANE AVOBENZNOE Parseal-1789 4-TERT-BUTYL-4''-METHOXYDIBENZOYLMETHANE (AVOBENZONE) p-t-Butyl p-Methoxydibenzoymethane 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)-1,3-propanedione 4-Methoxy-4'-tert-butyldibenzoylmethane Pasol1789 1-(p-tert-Butylphenyl)-3-(p-methoxyphenyl)-1,3-propanedione 1-[4-(tert-Butyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione P-1789 Parsol A UV Absorber 1789 Avobenzone (>=98%) 2-(4-tert-Butylbenzoyl)-4'-methoxyacetophenone LGB-AVB UV Avobenzone Avobenzone Basic information Parsol 1789 (1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propandion) 1-(4-TERT-BUTYLPHENYL)-3-(4-METHOXYPHENYL) 1,3-PROPA 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)-1,3-propanedione > Butyl-methoxydibenzoylmethane (B-MDM). Sunblock, Parsol1789@100 μg/mL in MeOH