CHIR-090
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- ₹13628.68 - ₹54871.93
- Product name: CHIR-090
- CAS: 728865-23-4
- MF: C24H27N3O5
- MW: 437.49
- EINECS:
- MDL Number:MFCD22665727
- Synonyms:CHIR-090;N-[(1S,2R)-2-Hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[[4-(4-morpholinylmethyl)phenyl]ethynyl]benzamide;N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide;CHIR-090 (CHIR 090;CS-2285;Benzamide, N-[(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]-;N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morphChemicalbookolin-4-ylmethyl)phenyl]ethynyl]benzamide;N-((2S,3R)-3-Hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML3092
- Product descriptionCHIR-090 ≥98% (HPLC)
- Packaging5MG
- Price₹13628.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML3092
- Product descriptionCHIR-090 ≥98% (HPLC)
- Packaging25MG
- Price₹54871.93
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML3092 | CHIR-090 ≥98% (HPLC) | 5MG | ₹13628.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML3092 | CHIR-090 ≥98% (HPLC) | 25MG | ₹54871.93 | 2022-06-14 | Buy |
Properties
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥21.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :9.11±0.40(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :≥21.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :9.11±0.40(Predicted)
color :White to off-white
Safety Information
| Symbol(GHS): |
 
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Description
CHIR-090 is the first reported compound that in fact kills both E. coli and Pseudomonas aeruginosa in bacterial disk diffusion assays (Liang et al. 2011). Nonetheless, CHIR-090 was about 600-fold less effective against LpxC orthologs from the Rhizobiaceae family than against E. coli LpxC. In this way, studies have shown that the removal of morpholine ring, based on a chemical scaffold of reduced radius, was able to increase affinity by 20-fold for LpxC enzymes from the Rhizobiaceae family of bacteria and enhance the antibiotic activity against E. coli and P. aeruginosa by 2–4 fold over CHIR-090.Related product price
- 76543-27-6
₹13953.43
![N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzamide](https://img.chemicalbook.com/ProductImageEN/2019-12/small/6071f2ba-f93d-486f-9cdb-74f52151c90f.png){kind=small}