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ChemicalBook > Product Catalogue >API >Urinary System Drugs >Diuretics Drugs >Chlorothiazide

Chlorothiazide

Chlorothiazide Structure
  • ₹8508.45 - ₹21985.58
  • Product name: Chlorothiazide
  • CAS: 58-94-6
  • MF: C7H6ClN3O4S2
  • MW: 295.72
  • EINECS:200-404-9
  • MDL Number:MFCD00058576
  • Synonyms:2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-,1,1-dioxide ;Aldoclor;Alurene;Chloriazid;Chlorosal;Chlorothiazid;Chlorthiazide
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 500MG
  • 50G
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1179
  • Product descriptionChlorothiazide Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹8508.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC4911
  • Product descriptionChlorothiazide thiazide diuretic
  • Packaging50G
  • Price₹21985.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1179 Chlorothiazide Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹8508.45 2022-06-14 Buy
Sigma-Aldrich(India) C4911 Chlorothiazide thiazide diuretic 50G ₹21985.58 2022-06-14 Buy

Properties

Melting point :342-343°C
Boiling point :608.8±65.0 °C(Predicted)
Density :1.7303 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Very Slightly, Heated)
form :Solid
pka :6.85, 9.45(at 25℃)
color :White to Off-White
Water Solubility :<0.1 g/100 mL at 19.5 ºC
Merck :14,2168
BCS Class :4
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :-0.240
CAS DataBase Reference :58-94-6(CAS DataBase Reference)
NIST Chemistry Reference :Chlorothiazide(58-94-6)
EPA Substance Registry System :Chlorothiazide (58-94-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Chlorothiazide is a first-in-class thiazide diuretic initially discovered from its ability to inhibit carbonic anhydrase in vitro. As an antihypertensive agent, this thiazide increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.

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Suppliers and manufacturers

KARPSCHEM LABORATORIES CTX Lifesciences Pvt Ltd Vasoya Industries Pvt Ltd Gland Pharma Ltd Medinex Laboratories Pvt Ltd Medinex Laboratories Pvt. Ltd. Anant Pharmaceuticals Pvt., Ltd. GLAND PHARMA LTD Innovative Synthetic Molecules Cambrex Corporation (Zenara)