Clotrimazole
- ₹3700 - ₹88277.88
- Product name: Clotrimazole
- CAS: 23593-75-1
- MF: C22H17ClN2
- MW: 344.84
- EINECS:245-764-8
- MDL Number:MFCD00057220
- Synonyms:myclo;(2-Chlorophenyl)diphenyl-1-imidazolylmethane;(Chlorotrityl)imidazole;1-((2-chlorophenyl)diphenylmethyl)-1h-imidazol ;1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole;1-(o-chloro-alpha,alpha-diphenylbenzyl)-imidazol ;1-[(2-chlorophenyl)diphenylmethyl]-1h-imidazol ;1-(o-Chloro-α,α-diphenylbenzyl)imidazole
7 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 100MG
- 1G
- 5G
- 25G
- 100G
- ManufacturerTCI Chemicals (India)
- Product numberC2867
- Product descriptionClotrimazole
- Packaging5G
- Price₹3700
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1058
- Product descriptionClotrimazole Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹8356.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number33894
- Product descriptionClotrimazole VETRANAL?, analytical standard
- Packaging100MG
- Price₹9309.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC6019
- Product descriptionClotrimazole
- Packaging5G
- Price₹10143.03
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC2867
- Product descriptionClotrimazole
- Packaging25G
- Price₹13400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC6019
- Product descriptionClotrimazole
- Packaging25G
- Price₹32388.4
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC6019
- Product descriptionClotrimazole
- Packaging100G
- Price₹88277.88
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | C2867 | Clotrimazole | 5G | ₹3700 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | PHR1058 | Clotrimazole Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹8356.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 33894 | Clotrimazole VETRANAL?, analytical standard | 100MG | ₹9309.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C6019 | Clotrimazole | 5G | ₹10143.03 | 2022-06-14 | Buy |
TCI Chemicals (India) | C2867 | Clotrimazole | 25G | ₹13400 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | C6019 | Clotrimazole | 25G | ₹32388.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C6019 | Clotrimazole | 100G | ₹88277.88 | 2022-06-14 | Buy |
Properties
Melting point :147-149°C
Boiling point :501.14°C (rough estimate)
Density :1.1095 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :2-8°C
solubility :Soluble in chloroform, DMSO, DMF and alcohols
pka :pKa 4.7(EtOH 50%aq ) (Uncertain)
form :Solid
color :White to Almost white
Water Solubility :<10mg/L(25 ºC)
λmax :556nm(Phosphate buffer sol.)(lit.)
Merck :14,2417
InChI :InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChIKey :VNFPBHJOKIVQEB-UHFFFAOYSA-N
SMILES :C1N(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CN=1
NIST Chemistry Reference :Clotrimazole(23593-75-1)
Boiling point :501.14°C (rough estimate)
Density :1.1095 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :2-8°C
solubility :Soluble in chloroform, DMSO, DMF and alcohols
pka :pKa 4.7(EtOH 50%aq ) (Uncertain)
form :Solid
color :White to Almost white
Water Solubility :<10mg/L(25 ºC)
λmax :556nm(Phosphate buffer sol.)(lit.)
Merck :14,2417
InChI :InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChIKey :VNFPBHJOKIVQEB-UHFFFAOYSA-N
SMILES :C1N(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CN=1
NIST Chemistry Reference :Clotrimazole(23593-75-1)
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections. It tightly binds sterol 14-α demethylase isoform B from A. fumigatus (KD = 103 nM) and, like other imidazoles, disturbs the fungal cell membrane. In mammalian cells, clotrimazole potently inhibits the calcium-dependent potassium channels Kv1.3 and IK-1 (IC50 = 6.0 and 0.07 μM, respectively).More related product prices
Chlorodimethylphenylsilane N-(Trimethylsilyl)imidazole Imidazole 1-Methylimidazole Biphenyl Methyltriphenylphosphonium bromide 138-24-9 42074-68-0Related product price
- Chlorodimethylphenylsilane
₹2400-13466.3 - N-(Trimethylsilyl)imidazole
₹890-46460.9 - Imidazole
₹234-112157.83