CLOZAPINE N-OXIDE
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- ₹21134.4 - ₹21173.7
- Product name: CLOZAPINE N-OXIDE
- CAS: 34233-69-7
- MF: C18H19ClN4O
- MW: 342.82
- EINECS:
- MDL Number:MFCD00210190
- Synonyms:e)(1,4)diazepine,8-chloro-11-(4-methyl-1-piperazinyl)-5h-dibenzo(n-oxide ;CLOZAPINE N-OXIDE;8-CHLORO-11-[4-METHYL-1-PIPERAZINYL]-5H-DIBENZO[B,E][1,4]DIAZEPINE N-OXIDE;MAJORMETABOLITEOFCLOZAPINE.POSSESSESLITTLEORNOACTIVITYAT5-HTRECEPTORS;Clozapine N-oxide Methanol Adduct;Clozapine N-oxide solution;Clozapine N-oxide (CNO);8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberC0832
- Product descriptionClozapine N-oxide
- Packaging5MG
- Price₹21173.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2304
- Product descriptionClozapine N-oxide hydrochloride ≥98% (HPLC), Water soluble Clozapine N-oxide
- Packaging5MG
- Price₹21134.4
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C0832 | Clozapine N-oxide | 5MG | ₹21173.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML2304 | Clozapine N-oxide hydrochloride ≥98% (HPLC), Water soluble Clozapine N-oxide | 5MG | ₹21134.4 | 2022-06-14 | Buy |
Properties
Melting point :190-248°C
Flash point :9℃
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Soluble in DMSO.
form :powder
pka :6.86±0.20(Predicted)
color :Yellow
biological source :synthetic
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :OGUCZBIQSYYWEF-UHFFFAOYSA-N
Flash point :9℃
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Soluble in DMSO.
form :powder
pka :6.86±0.20(Predicted)
color :Yellow
biological source :synthetic
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :OGUCZBIQSYYWEF-UHFFFAOYSA-N
Safety Information
Symbol(GHS): |
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Signal word: | Danger | |||||||||||||||||||||
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Description
Clozapine is an atypical anti-psychotic compound that modulates a range of neurological receptors. Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drug, also known as DREADD, technology to modulate synthetic receptors in vivo.Related product price
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