Costunolide
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- ₹9000 - ₹43830.43
- Product name: Costunolide
- CAS: 553-21-9
- MF: C15H20O2
- MW: 232.32
- EINECS:
- MDL Number:MFCD00210262
- Synonyms:(3AS,6E,10E,11AR)-3A,4,5,8,9,11A-HEXAHYDRO-6,10-DIMETHYL-3-METHYLENE-CYCLODECA[B]FURAN-2(3H)-ONE;COSTUNOLIDE;(e,e)-6-alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oicacidgamma-lactone ;germacra-1(10),4,11(13)-trien-12-oicacid,6-alpha-hydroxy-,gamma-lactone,(e, ;Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3- methylene-, [3aS-(3aR*,6E,10E,11aS*)]-;CUSTUNOLIDE;Cyclodeca[b]furan-2(3H)-one,3a,4,5,8,9,11a-;hexahydro-6,10-dimethyl-3-methylene-,(3aS,6E,10E,11aR)-
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberC2921
- Product descriptionCostunolide
- Packaging25MG
- Price₹9000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC2921
- Product descriptionCostunolide
- Packaging100MG
- Price₹15700
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0417
- Product descriptionCostunolide ≥97% (HPLC)
- Packaging5MG
- Price₹10727.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0417
- Product descriptionCostunolide ≥97% (HPLC)
- Packaging25MG
- Price₹43830.43
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | C2921 | Costunolide | 25MG | ₹9000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C2921 | Costunolide | 100MG | ₹15700 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML0417 | Costunolide ≥97% (HPLC) | 5MG | ₹10727.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0417 | Costunolide ≥97% (HPLC) | 25MG | ₹43830.43 | 2022-06-14 | Buy |
Properties
Melting point :106-107 °C
Boiling point :385.4±42.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
color :white to beige
InChI :InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1
InChIKey :HRYLQFBHBWLLLL-GRFSRWIASA-N
SMILES :O1C(=O)C(=C)[C@]2([H])CCC(C)=CCCC(C)=C[C@@]12[H] |t:10,15|
LogP :4.049 (est)
CAS DataBase Reference :553-21-9(CAS DataBase Reference)
NIST Chemistry Reference :Germacra-1(10),4,11(13)-trien-12-oic acid, 6«alpha»-hydroxy-, «gamma»-lactone, (e,e)-(553-21-9)
Boiling point :385.4±42.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
color :white to beige
InChI :InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1
InChIKey :HRYLQFBHBWLLLL-GRFSRWIASA-N
SMILES :O1C(=O)C(=C)[C@]2([H])CCC(C)=CCCC(C)=C[C@@]12[H] |t:10,15|
LogP :4.049 (est)
CAS DataBase Reference :553-21-9(CAS DataBase Reference)
NIST Chemistry Reference :Germacra-1(10),4,11(13)-trien-12-oic acid, 6«alpha»-hydroxy-, «gamma»-lactone, (e,e)-(553-21-9)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Costunolide is a sesquiterpene lactone that is found naturally in certain plant extracts and in alternative medicine oils. It reduces growth (EC50 = 3-35 μM) and induces apoptosis in assorted cancer cell lines. Costunolide inhibits the activation of Akt (15 μM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells (EC50 = 10 μM). It also inhibits telomerase activity in NALM-6 cells.More related product prices
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