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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Esters >Other esters >Coumarin 120

Coumarin 120

Coumarin 120 Structure
  • ₹3030 - ₹19771
  • Product name: Coumarin 120
  • CAS: 26093-31-2
  • MF: C10H9NO2
  • MW: 175.18
  • EINECS:247-454-8
  • MDL Number:MFCD00006868
  • Synonyms:7-Amino-4-methyl-2H-chromen-2-one, 7-Amino-4-methyl-2-oxo-2H-chromene, 7-Amino-4-methyl-2-oxo-2H-1-benzopyran;Coumarin 120, AMC;(2S,5R,6R)-6-[(2R)-2-aMino-2-(4-hydroxyphenyl)acetaMido]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;7-AMino-4-MethylcouMarin 7-AMino-4-MethylcouMarin, pure, 98% 1GR;7-AMino-4-MethylcouMarin 99%;7-Amino-4-methylcoumarin≥ 98% (HPLC);BUTTPARK 44\02-66
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Brand

  • Sigma-Aldrich(India)
  • ALFA India
  • TCI Chemicals (India)
  • SRL

Package

  • 10MG
  • 100MG
  • 250MG
  • 500MG
  • 1G
  • 5g
  • 1Gms
  • ManufacturerSigma-Aldrich(India)
  • Product number257370
  • Product description7-Amino-4-methylcoumarin 99%
  • Packaging100MG
  • Price₹5971.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number164545
  • Product description7-Amino-4-methylcoumarin - CAS 26093-31-2 - Calbiochem Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity.
  • Packaging10MG
  • Price₹8420
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9891
  • Product description7-Amino-4-methylcoumarin Chromophore for substrates
  • Packaging500MG
  • Price₹8813.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9891
  • Product description7-Amino-4-methylcoumarin Chromophore for substrates
  • Packaging250MG
  • Price₹11388.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number257370
  • Product description7-Amino-4-methylcoumarin 99%
  • Packaging500MG
  • Price₹11599.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9891
  • Product description7-Amino-4-methylcoumarin Chromophore for substrates
  • Packaging1G
  • Price₹14674.2
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A15017-06
  • Product description7-Amino-4-methylcoumarin, 98%
  • Packaging5g
  • Price₹19771
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A15017-03
  • Product description7-Amino-4-methylcoumarin, 98%
  • Packaging1g
  • Price₹7500
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A15017-MD
  • Product description7-Amino-4-methylcoumarin, 98%
  • Packaging250mg
  • Price₹4555
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0760
  • Product description7-Amino-4-methylcoumarin [for HPLC Labeling]
  • Packaging1G
  • Price₹7500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM0760
  • Product description7-Amino-4-methylcoumarin [for HPLC Labeling]
  • Packaging5G
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number74880
  • Product description7-Amino-4-Methylcoumarin (7-AMC) extrapure, 99%
  • Packaging1Gms
  • Price₹3030
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 257370 7-Amino-4-methylcoumarin 99% 100MG ₹5971.8 2022-06-14 Buy
Sigma-Aldrich(India) 164545 7-Amino-4-methylcoumarin - CAS 26093-31-2 - Calbiochem Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity. 10MG ₹8420 2022-06-14 Buy
Sigma-Aldrich(India) A9891 7-Amino-4-methylcoumarin Chromophore for substrates 500MG ₹8813.4 2022-06-14 Buy
Sigma-Aldrich(India) A9891 7-Amino-4-methylcoumarin Chromophore for substrates 250MG ₹11388.6 2022-06-14 Buy
Sigma-Aldrich(India) 257370 7-Amino-4-methylcoumarin 99% 500MG ₹11599.5 2022-06-14 Buy
Sigma-Aldrich(India) A9891 7-Amino-4-methylcoumarin Chromophore for substrates 1G ₹14674.2 2022-06-14 Buy
ALFA India ALF-A15017-06 7-Amino-4-methylcoumarin, 98% 5g ₹19771 2022-05-26 Buy
ALFA India ALF-A15017-03 7-Amino-4-methylcoumarin, 98% 1g ₹7500 2022-05-26 Buy
ALFA India ALF-A15017-MD 7-Amino-4-methylcoumarin, 98% 250mg ₹4555 2022-05-26 Buy
TCI Chemicals (India) M0760 7-Amino-4-methylcoumarin [for HPLC Labeling] 1G ₹7500 2022-05-26 Buy
TCI Chemicals (India) M0760 7-Amino-4-methylcoumarin [for HPLC Labeling] 5G ₹14800 2022-05-26 Buy
SRL 74880 7-Amino-4-Methylcoumarin (7-AMC) extrapure, 99% 1Gms ₹3030 2022-05-26 Buy

Properties

Melting point :223-226 °C (lit.)
Boiling point :306.47°C (rough estimate)
Density :1.1999 (rough estimate)
refractive index :1.5060 (estimate)
storage temp. :2-8°C
solubility :Soluble in acetone (10 mg/ml) dimethyl sulfoxide (10 mg/ml) and dimethylformamide.
form :Crystalline Powder
pka :1.89 ± 0.20, most basic, temperature: 25 °C
color :Beige to brown
Sensitive :Light Sensitive
λmax :351 nm (MeOH); 342 nm (Buffer pH 7)
BRN :142231
Major Application :For authentification; dyelasers; color display devices; inks;monitoring underlying corrosion on coated aluminum;photoinitiating systems; recording materials;semiconductor devices; dye-sensitized solar cells(DSCs); mesoporous silica fibers; SiO2 sonogelhybrid materials; textiles; waveguides;whitening agents,
Biological Applications :Identifyingbacteria; measuring urinary kallikrein levels;monitoring platinum(iv) reduction and platinum(ii)reactions in cancer cells; as a substrate for measuringadipinylamidases activity, aromatic amino aciddecarboxylases activity, histone deacetylasesactivity, hydrolases/esterases activity,β-lactamases activity, microbial nitroreductasesactivity, penicillin G acylases activity,proteases/proteinases/peptidases activity,glutamyltransferases activity, tryptophanasesactivity; as an effective antitubercular agent; use astemperature sensor,
InChIKey :GLNDAGDHSLMOKX-UHFFFAOYSA-N
CAS DataBase Reference :26093-31-2(CAS DataBase Reference)
NIST Chemistry Reference :Coumarin, 7-amino-4-methyl-(26093-31-2)
EPA Substance Registry System :2H-1-Benzopyran-2-one, 7-amino-4-methyl- (26093-31-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Used as matrix for analysis of monosulfated disaccharides and as a co-matrix with 6-aza-2-thiothymidine for sulfated neutral and salivated tri-and tetrasaccharides. Reagent for preparing new fluorogenic AMC-based substrates for cystine amino peptidase (and other hydrolases). Also used as reference compound in the enzyme assay.

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