ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Esters >Other esters >Coumarin 120
Coumarin 120
- CAS No.
- 26093-31-2
- Chemical Name:
- Coumarin 120
- Synonyms
- AMC;7-AMINO-4-METHYL-2H-CHROMEN-2-ONE;7-AMINO-4-METHYLCOUMARIN;C120;AMC 7-Amino-4-Methylcoumarin;2H-1-Benzopyran-2-one, 7-amino-4-methyl-;H-MCA;C 120;7-AMC;NSC 45796
- CBNumber:
- CB4354765
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MOL File:
- 26093-31-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/12 14:52:38
| Melting point | 223-226 °C (lit.) |
|---|---|
| Boiling point | 306.47°C (rough estimate) |
| Density | 1.1999 (rough estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in acetone (10 mg/ml) dimethyl sulfoxide (10 mg/ml) and dimethylformamide. |
| form | Crystalline Powder |
| pka | 1.89 ± 0.20, most basic, temperature: 25 °C |
| color | Beige to brown |
| Sensitive | Light Sensitive |
| λmax | 351 nm (MeOH); 342 nm (Buffer pH 7) |
| BRN | 142231 |
| Major Application | For authentification; dyelasers; color display devices; inks;monitoring underlying corrosion on coated aluminum;photoinitiating systems; recording materials;semiconductor devices; dye-sensitized solar cells(DSCs); mesoporous silica fibers; SiO2 sonogelhybrid materials; textiles; waveguides;whitening agents, |
| Biological Applications | Identifyingbacteria; measuring urinary kallikrein levels;monitoring platinum(iv) reduction and platinum(ii)reactions in cancer cells; as a substrate for measuringadipinylamidases activity, aromatic amino aciddecarboxylases activity, histone deacetylasesactivity, hydrolases/esterases activity,β-lactamases activity, microbial nitroreductasesactivity, penicillin G acylases activity,proteases/proteinases/peptidases activity,glutamyltransferases activity, tryptophanasesactivity; as an effective antitubercular agent; use astemperature sensor, |
| InChIKey | GLNDAGDHSLMOKX-UHFFFAOYSA-N |
| CAS DataBase Reference | 26093-31-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Coumarin, 7-amino-4-methyl-(26093-31-2) |
| EPA Substance Registry System | 2H-1-Benzopyran-2-one, 7-amino-4-methyl- (26093-31-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 32049000 | |||||||||
| NFPA 704 |
|
Coumarin 120 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A9891 | 7-Amino-4-methylcoumarin Chromophore for substrates | 26093-31-2 | 500MG | ₹8813.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9891 | 7-Amino-4-methylcoumarin Chromophore for substrates | 26093-31-2 | 250MG | ₹11388.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A9891 | 7-Amino-4-methylcoumarin Chromophore for substrates | 26093-31-2 | 1G | ₹14674.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 257370 | 7-Amino-4-methylcoumarin 99% | 26093-31-2 | 100MG | ₹5971.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 257370 | 7-Amino-4-methylcoumarin 99% | 26093-31-2 | 500MG | ₹11599.5 | 2022-06-14 | Buy |
Coumarin 120 Chemical Properties,Uses,Production
Chemical Properties
Coumarin 120 is Light yellow beige powder
Uses
Coumarin 120 is widely used fluorophore, well-known for preparing fluorogenic substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
General Description
7-Amino-4-methylcoumarin (coumarin120) is an aminocoumarin laser dye that can emit laser in the range of 370-760 nm. It has three intermolecular hydrogen bonded structures with C-H···O and N-H····O.
Purification Methods
Dissolve it in 5% HCl, filter and basify with 2M ammonia. The precipitate is dried in a vacuum and recrystallised from dilute EtOH. It yields a blue solution and is light sensitive. [Sigler Synthesis 614 1980, Kanaoka et al. Chem Pharm Bull Jpn 30 1485 1982, Beilstein 18/11 V 445.]
Coumarin 120 Preparation Products And Raw materials
Raw materials
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Global( 432)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| chromsynth pvt ltd | +919704220374 | Hyderabad, India | 244 | 58 | Inquiry |
| Hyderabad | +91-9676447615 +91-9676447615 | Telangana, India | 192 | 58 | Inquiry |
| Biosyn Research Chemicals | +91-91-9346022300 +91-9346022300 | Telangana, India | 465 | 58 | Inquiry |
| SVH BIOSCIENCES | +91-6303499280 +91-6303499280 | Hyderabad, India | 478 | 58 | Inquiry |
| chakrachem Lifesciences | +91 9902744663 | Hyderabad, India | 451 | 58 | Inquiry |
| CHEMAZON LABORATORIES | +91 9848551964 | Hyderabad, India | 1320 | 58 | Inquiry |
| AVIGYABIOSCIENCES PRIVATE LIMITED | +91-9849533087 +91-9849533087 | Telangana, India | 156 | 58 | Inquiry |
| Dr R R Organics | +91-9666306440 +91-9666306440 | Telangana, India | 267 | 58 | Inquiry |
| BASR Fine Chemicals Pvt. Ltd. | +91-9848230391 +91-9848230391 | Telangana, India | 908 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| chromsynth pvt ltd | 58 |
| Hyderabad | 58 |
| Biosyn Research Chemicals | 58 |
| SVH BIOSCIENCES | 58 |
| chakrachem Lifesciences | 58 |
| CHEMAZON LABORATORIES | 58 |
| AVIGYABIOSCIENCES PRIVATE LIMITED | 58 |
| Dr R R Organics | 58 |
| BASR Fine Chemicals Pvt. Ltd. | 58 |
26093-31-2(Coumarin 120)Related Search:
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Coumarin 120, AMC
(2S,5R,6R)-6-[(2R)-2-aMino-2-(4-hydroxyphenyl)acetaMido]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
7-AMino-4-MethylcouMarin
7-AMino-4-MethylcouMarin, pure, 98% 1GR
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7-Amino-4-methylcoumarin, 99%, laser grade, pure
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7-Amino-4-methylcumarin
C 120
Coumarin,7-amino-4-methyl-
Cumarin120
7-AMINO-4-METHYLCOUMARIN 99% (LASER DY&
7-AMINO-4-METHYLCOUMARIN, FOR FLUOR-ESCE NCE
7-AMINO-4-METHYLCOUMARIN, 99% (LASER DYE )
7-AMINO-4-METHYLCOUMARIN (AMC)
7-Amino-4-methyl-2H-1-benzopyran-2-one
7-Amino-4-methylcoumarin, laser grade, pure, 99%
7-Amino-4-methylcoumarin, pure, 98%
7-AMINO-4-METHYLCOUMARIN 98.5% MIN
AMANTADINESULFATE
AMC, 98.5% MIN.
(4-Methyl-2-oxo-2H-chromen-7-yl)amine
7-AMC
NSC 45796
7-Amino-4-methylcoumarin [for HPLC Labeling]
7-Amino-4-methylcoumarin, 98%, pure
7-Amino-4-methylcoumarin - CAS 26093-31-2 - Calbiochem
Amino Labeling
7-Amino-4-methylcoumarin[forHPLCLabeling]>
7-Amino-4-Methylcoumarin (7-AMC) extrapure, 99%
AMC [7-Amino-4-methylcoumarin] *CAS 26093-31-2*
7-Amino-4-methylcoumarin, 97.5%
AMC
7-AMINO-4-METHYL-2H-CHROMEN-2-ONE
2H-1-Benzopyran-2-one, 7-amino-4-methyl-
C120
AMC 7-Amino-4-Methylcoumarin
7-AMINO-4-METHYLCOUMARIN
Coumarine120
Hymecromone Impurity 9
26093-31-2
Fluorescent Probes, Labels, Particles and Stains
Fluorogenic