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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Androgen and anabolic hormones >Danazol

Danazol

Danazol  Structure
  • ₹9277.03 - ₹59862.25
  • Product name: Danazol
  • CAS: 17230-88-5
  • MF: C22H27NO2
  • MW: 337.46
  • EINECS:241-270-1
  • MDL Number:MFCD00056838
  • Synonyms:DANZOL;DANAZOL;17alpha-pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol;(17A)-PREGNA-2,4-DIEN-20-YNO[2,3-D]ISOXAZOL-17-OL;17BETA-HYDROXY-2,4,17ALPHA-PREGNADIEN-20-YNO[2,3-D]ISOXAZOLE;17a-Ethynyl-17b- hydroxy-4-androsteno[2,3-d]isoxazole;Bonzol;Cyclomen
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 250MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberD8399
  • Product descriptionDanazol ≥98%
  • Packaging100MG
  • Price₹9277.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD8399
  • Product descriptionDanazol ≥98%
  • Packaging250MG
  • Price₹20621.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD8399
  • Product descriptionDanazol ≥98%
  • Packaging1G
  • Price₹59862.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D8399 Danazol ≥98% 100MG ₹9277.03 2022-06-14 Buy
Sigma-Aldrich(India) D8399 Danazol ≥98% 250MG ₹20621.63 2022-06-14 Buy
Sigma-Aldrich(India) D8399 Danazol ≥98% 1G ₹59862.25 2022-06-14 Buy

Properties

Melting point :224.4-226.80C
alpha :D25 +7.5° (ethanol); D25 +21.9° (chloroform)
Boiling point :473.76°C (rough estimate)
Density :1.0909 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :-20°C Freezer
solubility :Acetonitrile (Slightly), Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka :13.10±0.60(Predicted)
form :Solid
color :White to Pale Yellow
Water Solubility :Partly soluble in water. Soluble in chloroform (25 mg/ml), acetone, acetonitrile, and ethanol. 17beta-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole and 2,4,17a-Pregnadien-20-yno[2,3-d]isoxazol-17-ol are the synonym of this compound.
EPA Substance Registry System :Danazol (17230-88-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Danazol is a derivative of testosterone and ethisterone that can bind to androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone. It possesses weak androgenic effects and inhibits the production of gonadotropins. It has been used to address symptoms of endometriosis and to inhibit the growth of endocrine-responsive pancreatic and breast cancer cells but has also been linked to the development of ovarian cancer.

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