DEMECOLCINE
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- ₹2889 - ₹101083.85
- Product name: DEMECOLCINE
- CAS: 477-30-5
- MF: C21H25NO5
- MW: 371.43
- EINECS:207-514-6
- MDL Number:MFCD00075459
- Synonyms:substancef ;Colcemide;DEMECOLCINE HYBRI-MAXR;Colcemid-D3=Demecolcine-D3;N-Deacetyl-N-methyl(deutero)colchicine;COLCEMIDE(R);COLCEMID(R);DEMECOLCIN
8 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- ottokemi
Package
- 5MG
- 10MG
- 25mg
- 50MG
- 20ML
- 100ML
- ManufacturerSigma-Aldrich(India)
- Product numberD1925
- Product descriptionDemecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra
- Packaging20ML
- Price₹6105.3
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD1925
- Product descriptionDemecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra
- Packaging100ML
- Price₹10294.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD7385
- Product descriptionDemecolcine ≥98% (HPLC)
- Packaging5MG
- Price₹18294.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD7385
- Product descriptionDemecolcine ≥98% (HPLC)
- Packaging10MG
- Price₹31219.3
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD7385
- Product descriptionDemecolcine ≥98% (HPLC)
- Packaging50MG
- Price₹101083.85
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number D 0021
- Product descriptionDemecolcine, ≥98%+
- Packaging10mg
- Price₹2889
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number D 0021
- Product descriptionDemecolcine, ≥98%+
- Packaging5mg
- Price₹16803
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number D 0021
- Product descriptionDemecolcine, ≥98%+
- Packaging25mg
- Price₹60705
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D1925 | Demecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra | 20ML | ₹6105.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D1925 | Demecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra | 100ML | ₹10294.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D7385 | Demecolcine ≥98% (HPLC) | 5MG | ₹18294.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D7385 | Demecolcine ≥98% (HPLC) | 10MG | ₹31219.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D7385 | Demecolcine ≥98% (HPLC) | 50MG | ₹101083.85 | 2022-06-14 | Buy |
ottokemi | D 0021 | Demecolcine, ≥98%+ | 10mg | ₹2889 | 2022-05-26 | Buy |
ottokemi | D 0021 | Demecolcine, ≥98%+ | 5mg | ₹16803 | 2022-05-26 | Buy |
ottokemi | D 0021 | Demecolcine, ≥98%+ | 25mg | ₹60705 | 2022-05-26 | Buy |
Properties
Melting point :73-75°C
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Colcemid is a colchicine derivative that inhibits tubulin polymerization as potently as colchicine (IC50 = 2.1 and 2.4 μM, respectively) but is less toxic. At very low (nanomolar) concentrations, colcemid suppresses microtubule dynamicity and inhibits cell migration, while at micromolar levels it blocks microtubule assembly, arresting cells in metaphase. Mitotic block by colcemid is used to synchronize cells and for karyotyping in cytogenetic studies. Prolonged exposure to colcemid can activate p53, leading to apoptosis.More related product prices
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