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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Natural sources of antineoplastic >DEMECOLCINE

DEMECOLCINE

DEMECOLCINE Structure
  • ₹2889 - ₹101083.85
  • Product name: DEMECOLCINE
  • CAS: 477-30-5
  • MF: C21H25NO5
  • MW: 371.43
  • EINECS:207-514-6
  • MDL Number:MFCD00075459
  • Synonyms:substancef ;Colcemide;DEMECOLCINE HYBRI-MAXR;Colcemid-D3=Demecolcine-D3;N-Deacetyl-N-methyl(deutero)colchicine;COLCEMIDE(R);COLCEMID(R);DEMECOLCIN
Price8 Properties Safety Information Description
8 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 5MG
  • 10MG
  • 25mg
  • 50MG
  • 20ML
  • 100ML
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1925
  • Product descriptionDemecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra
  • Packaging20ML
  • Price₹6105.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1925
  • Product descriptionDemecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra
  • Packaging100ML
  • Price₹10294.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD7385
  • Product descriptionDemecolcine ≥98% (HPLC)
  • Packaging5MG
  • Price₹18294.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD7385
  • Product descriptionDemecolcine ≥98% (HPLC)
  • Packaging10MG
  • Price₹31219.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD7385
  • Product descriptionDemecolcine ≥98% (HPLC)
  • Packaging50MG
  • Price₹101083.85
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number D 0021
  • Product descriptionDemecolcine, ≥98%+
  • Packaging10mg
  • Price₹2889
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 0021
  • Product descriptionDemecolcine, ≥98%+
  • Packaging5mg
  • Price₹16803
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 0021
  • Product descriptionDemecolcine, ≥98%+
  • Packaging25mg
  • Price₹60705
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D1925 Demecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra 20ML ₹6105.3 2022-06-14 Buy
Sigma-Aldrich(India) D1925 Demecolcine solution 10?μg/mL in HBSS, ACF Qualified, BioXtra 100ML ₹10294.58 2022-06-14 Buy
Sigma-Aldrich(India) D7385 Demecolcine ≥98% (HPLC) 5MG ₹18294.25 2022-06-14 Buy
Sigma-Aldrich(India) D7385 Demecolcine ≥98% (HPLC) 10MG ₹31219.3 2022-06-14 Buy
Sigma-Aldrich(India) D7385 Demecolcine ≥98% (HPLC) 50MG ₹101083.85 2022-06-14 Buy
ottokemi D 0021 Demecolcine, ≥98%+ 10mg ₹2889 2022-05-26 Buy
ottokemi D 0021 Demecolcine, ≥98%+ 5mg ₹16803 2022-05-26 Buy
ottokemi D 0021 Demecolcine, ≥98%+ 25mg ₹60705 2022-05-26 Buy

Properties

Melting point :73-75°C
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Colcemid is a colchicine derivative that inhibits tubulin polymerization as potently as colchicine (IC50 = 2.1 and 2.4 μM, respectively) but is less toxic. At very low (nanomolar) concentrations, colcemid suppresses microtubule dynamicity and inhibits cell migration, while at micromolar levels it blocks microtubule assembly, arresting cells in metaphase. Mitotic block by colcemid is used to synchronize cells and for karyotyping in cytogenetic studies. Prolonged exposure to colcemid can activate p53, leading to apoptosis.

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Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd
DEMECOLCINE
₹1.00 /1KG
DEMECOLCINE CAS:477-30-5
Henan Fengda Chemical Co., Ltd
DEMECOLCINE
₹1.00 /100KG
DEMECOLCINE CAS:477-30-5
career henan chemical co
DEMECOLCINE
₹3.00 /1KG
DEMECOLCINE CAS:477-30-5
Otto Chemie Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates CLEARSYNTH LABS LTD. A.J Chemicals
TargetMol Chemicals Inc.
ANHUI WITOP BIOTECH CO., LTD