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ChemicalBook > Product Catalogue >Organic Chemistry >Inorganic acid Esters >Dimethyl sulfate

Dimethyl sulfate

Dimethyl sulfate Structure
  • ₹441
  • Product name: Dimethyl sulfate
  • CAS: 77-78-1
  • MF: C2H6O4S
  • MW: 126.13
  • EINECS:201-058-1
  • MDL Number:MFCD00008416
  • Synonyms:sulfatededimethyle ;sulfatededimethyle(french) ;DIMETHYLSULFATE,REAGENT;Dimethylsulfate,98%;DIMETHYL SULFATE 99 % MIN.;DIMETHYL SULFATE MOLECULAR BIOLOGY*REAGE NT;DIMETHYL SULFATE 99+%;Dimethylsulphate99%
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Brand

  • ottokemi

Package

  • 500mL
  • Manufacturerottokemi
  • Product number D 2095
  • Product descriptionDimethyl sulphate 98%
  • Packaging500mL
  • Price₹441
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ottokemi D 2095 Dimethyl sulphate 98% 500mL ₹441 2022-05-26 Buy

Properties

Melting point :-32 °C
Boiling point :188 °C(lit.)
Density :1.333 g/mL at 25 °C(lit.)
vapor density :4.3 (vs air)
vapor pressure :0.7 mm Hg ( 25 °C)
refractive index :n20/D 1.386(lit.)
Flash point :182 °F
storage temp. :2-8°C
solubility :ethanol: 0.26 g/mL, clear, colorless
form :Liquid
color :Clear colorless
Odor :Almost odorless
Water Solubility :2.8 g/100 mL (18 ºC)
Merck :13,3282
BRN :635994
Exposure limits :TLV/PEL-TWA skin 0.1 ppm (0.52 mg/m3 ) (ACGIH, OSHA, NIOSH) IDLH 10 ppm (NIOSH).
Dielectric constant :55.0(20℃)
Stability :Stable; combustible. Incompatible with strong oxidizing agents, strong bases including ammonia. Moisture-sensitive.
CAS DataBase Reference :77-78-1(CAS DataBase Reference)
IARC :2A (Vol. 4, Sup 7, 71) 1999
NIST Chemistry Reference :Sulfuric acid, dimethyl ester(77-78-1)
EPA Substance Registry System :Dimethyl sulfate (77-78-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dimethyl sulfate (chemical formula: (CH3O)2SO2) is an odorless, corrosive, oily liquid which can release toxic fumes during heating. It can be synthesized through the esterification of sulfuric acid with methanol, and alternatively by the distillation of methyl hydrogen sulfate. In industry, dimethyl sulfate is used as a methylating agent for the manufacture of many organic chemicals. It can be used for methylation of phenols, amines, and thiol. Moreover, it can be used for base sequencing and DNA chain cleavage since it can rupture the imidazole rings present in guanine. It can also be used for protein-DNA interaction analysis. However, its vapor is toxic to eyes and lungs, can do harm to our body. It is a potential carcinogen based on known experimental data.

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