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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antidepressants, Antimanics drugs >Doxepin hydrochloride

Doxepin hydrochloride

Doxepin hydrochloride  Structure
  • ₹2407.3 - ₹22635.08
  • Product name: Doxepin hydrochloride
  • CAS: 1229-29-4
  • MF: C19H22ClNO
  • MW: 315.84
  • EINECS:214-966-8
  • MDL Number:MFCD00079135
  • Synonyms:11[16H]-[3-(DIMETHYLAMINO)-PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE;11-(3-dimethylaminopropylidene)-6,11-dihydro-benz[b,e]oxepin;11-(3-DIMETHYLAMINOPROPYLIDENE)-6,11-DIHYDRODIBENZ[B,E]OXEPIN HYDROCHLORIDE;Doxepine hydrochloride;1-Propanamine, 3-dibenzb,eoxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride;DOXEPINHYDROCHLORIDE,USP;11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepine hydrochloride;3-DIBENZ(B,C)OXEPIN 11(6H)YLIDENE-N,N-DIMETHYL-1-PROPANAMINE HYDROCHLORIDE
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1ML
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4626
  • Product descriptionDoxepin Hydrochloride (mixture of isomers)
  • Packaging1G
  • Price₹3400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4626
  • Product descriptionDoxepin Hydrochloride (mixture of isomers)
  • Packaging5G
  • Price₹9400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4626
  • Product descriptionDoxepin Hydrochloride (mixture of isomers)
  • Packaging25G
  • Price₹17900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD-927
  • Product descriptionDoxepin hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹2407.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD4526
  • Product descriptionDoxepin hydrochloride ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder
  • Packaging1G
  • Price₹6873.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD4526
  • Product descriptionDoxepin hydrochloride ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder
  • Packaging5G
  • Price₹22635.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4626 Doxepin Hydrochloride (mixture of isomers) 1G ₹3400 2022-05-26 Buy
TCI Chemicals (India) D4626 Doxepin Hydrochloride (mixture of isomers) 5G ₹9400 2022-05-26 Buy
TCI Chemicals (India) D4626 Doxepin Hydrochloride (mixture of isomers) 25G ₹17900 2022-05-26 Buy
Sigma-Aldrich(India) D-927 Doxepin hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹2407.3 2022-06-14 Buy
Sigma-Aldrich(India) D4526 Doxepin hydrochloride ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder 1G ₹6873.88 2022-06-14 Buy
Sigma-Aldrich(India) D4526 Doxepin hydrochloride ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder 5G ₹22635.08 2022-06-14 Buy

Properties

Melting point :187-189°C
Flash point :9℃
storage temp. :2-8°C
solubility :1 M HCl: 50 mg/mL
form :powder
color :white to off-white
Water Solubility :Soluble in water (100 mM), chloroform (1:2), alcohol (1:1), methanol, and DMSO.
λmax :298nm(lit.)
Merck :14,3435
Stability :Store in Freezer at -20°C
InChIKey :MHNSPTUQQIYJOT-SJDTYFKWSA-N
CAS DataBase Reference :1229-29-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Doxepin is a tricyclic antidepressant that inhibits the reuptake of serotonin and norepinephrine and acts as an antagonist at histamine, serotonin, adrenergic, and muscarinic receptors with Ki values in the nanomolar range.

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