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ChemicalBook > Product Catalogue >API >Antibiotics >Tetracycline drugs >Doxycycline hyclate

Doxycycline hyclate

Doxycycline hyclate Structure
  • ₹2260 - ₹100910.65
  • Product name: Doxycycline hyclate
  • CAS: 24390-14-5
  • MF: C24H31ClN2O9
  • MW: 526.97
  • EINECS:2017-001-1
  • MDL Number:MFCD06200253
  • Synonyms:4-(DIMETHYLAMINO)-1,4,4 ALPHA,5,5 ALPHA,6,11,12 ALPHA-OCTAHYDRO-3,5,10,12,12 ALPHA-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NAPHTHACENECARBOXAMIDE, MONOHYDRATE;4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NA;Doxycycline monohydrate BP2000/Ph Eur 4/USP25;DOXYCYCLINE HYDROCHLORIDE, VETRANAL;Doxycycline Hyclate USP;DOXYCYCLINE HYCLATE USP GRADE;(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamidehydrochloride;Doxycycline Hc1
12 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 100MG
  • 1G
  • 5G
  • 10G
  • 25G
  • 100G
  • 1Gms
  • 5Gms
  • 10Gms
  • ManufacturerTCI Chemicals (India)
  • Product numberD4116
  • Product descriptionDoxycycline Hyclate
  • Packaging5G
  • Price₹2400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4116
  • Product descriptionDoxycycline Hyclate
  • Packaging25G
  • Price₹8500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9891
  • Product descriptionDoxycycline hyclate
  • Packaging1G
  • Price₹5120.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number33429
  • Product descriptionDoxycycline hyclate VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹7415.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1145
  • Product descriptionDoxycycline hyclate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9839.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9891
  • Product descriptionDoxycycline hyclate
  • Packaging5G
  • Price₹15155
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9891
  • Product descriptionDoxycycline hyclate
  • Packaging10G
  • Price₹19733.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9891
  • Product descriptionDoxycycline hyclate
  • Packaging25G
  • Price₹26001.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9891
  • Product descriptionDoxycycline hyclate
  • Packaging100G
  • Price₹100910.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number65094
  • Product descriptionDoxycycline hyclate (DXH) for biochemistry & microbiology
  • Packaging10Gms
  • Price₹6530
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number65094
  • Product descriptionDoxycycline hyclate (DXH) for biochemistry & microbiology
  • Packaging5Gms
  • Price₹4390
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number65094
  • Product descriptionDoxycycline hyclate (DXH) for biochemistry & microbiology
  • Packaging1Gms
  • Price₹2260
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4116 Doxycycline Hyclate 5G ₹2400 2022-05-26 Buy
TCI Chemicals (India) D4116 Doxycycline Hyclate 25G ₹8500 2022-05-26 Buy
Sigma-Aldrich(India) D9891 Doxycycline hyclate 1G ₹5120.23 2022-06-14 Buy
Sigma-Aldrich(India) 33429 Doxycycline hyclate VETRANAL?, analytical standard 100MG ₹7415.13 2022-06-14 Buy
Sigma-Aldrich(India) PHR1145 Doxycycline hyclate Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9839.93 2022-06-14 Buy
Sigma-Aldrich(India) D9891 Doxycycline hyclate 5G ₹15155 2022-06-14 Buy
Sigma-Aldrich(India) D9891 Doxycycline hyclate 10G ₹19733.98 2022-06-14 Buy
Sigma-Aldrich(India) D9891 Doxycycline hyclate 25G ₹26001.65 2022-06-14 Buy
Sigma-Aldrich(India) D9891 Doxycycline hyclate 100G ₹100910.65 2022-06-14 Buy
SRL 65094 Doxycycline hyclate (DXH) for biochemistry & microbiology 10Gms ₹6530 2022-05-26 Buy
SRL 65094 Doxycycline hyclate (DXH) for biochemistry & microbiology 5Gms ₹4390 2022-05-26 Buy
SRL 65094 Doxycycline hyclate (DXH) for biochemistry & microbiology 1Gms ₹2260 2022-05-26 Buy

Properties

Melting point :206-209?C (dec.)
alpha :D25 -110° (c = 1 in 0.01N methanolic HCl)
RTECS :QI8925000
storage temp. :2-8°C
solubility :H2O: soluble50mg/mL
form :Yellow to yellow-green crystalline solid
color :yellow to greenish-yellow
Water Solubility :Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chloroform and ether.
Merck :14,3440
BRN :5702728
InChIKey :HALQELOKLVRWRI-VDBOFHIQSA-N
SMILES :C(O)C.O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:4,12,16,18,19,21,r|

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Doxycycline Hyclate is the hyclate salt form of doxycycline, is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 μM. It can be used as a regulator for inducible gene expression systems where expression depends on either the presence (Tet-On) or absence (Tet-Off) of doxycycline. Formulations containing doxycycline have been used in the treatment of bacterial infections and the prevention of malaria.

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