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ChemicalBook > Product Catalogue >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >edoxaban

edoxaban

edoxaban Structure
  • ₹0
  • Product name: edoxaban
  • CAS: 480449-70-5
  • MF: C24H30ClN7O4S
  • MW: 548.06
  • EINECS:859-181-7
  • MDL Number:MFCD13195544
  • Synonyms:EthanediaMide, N1-(5-chlo...;edoxaban;N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide;DU-176;Edoxaban(DU-176);Edoxaban N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide;5- chloro -2- pyridine -N, N-dimethyl formamidine;Edoxaban Tosylate Hydrate 2
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>213°C (dec.)
Density :1.43
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :9.46±0.70(Predicted)
form :Solid
color :White to Off-White
InChIKey :HGVDHZBSSITLCT-JLJPHGGASA-N
SMILES :C(NC1=NC=C(Cl)C=C1)(=O)C(N[C@H]1CC[C@H](C(N(C)C)=O)C[C@H]1NC(C1=NC2CCN(C)CC=2S1)=O)=O
LogP :-1.455

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Edoxaban is a direct factor Xa inhibitor. The inhibition of factor Xa in the coagulation cascade leads to an anticoagulant effect. Edoxaban is administered orally, at a dosage of 60 mg once daily, and the drug’s current proposed indication is for the prevention of stroke and systemic embolism in patients with AF.?

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Tranexamic acid Tetracaine hydrochloride SUCCINYLCHOLINE CHLORIDE EthanediaMide, N1-(5-chlo... Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- 2-Pyrimidinamine, N-(1-methylethyl)- (9CI) ISOXICAM Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride 2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 2-Amino-5-chloropyridine EthanediaMide, N1-(5-chlo... carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester 720720-96-7 Erlotinib hydrochloride Isoxepac Itraconazole Imatinib 2-Amino-6-chloropyridine 2-Amino-3-chloropyridine 2-Amino-4-chloropyridine

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Suppliers and manufacturers

Saptagir Laboratories PVT.LTD. Dr. Reddy's Laboratories Ltd Hikal Ltd. Ralington Pharma Ami Lifesciences Pvt Ltd Vijaya Pharma And Life Science Anlon Healthcare Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd Libertas SynZeal Research Pvt Ltd