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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Fumagillin

Fumagillin

Fumagillin Structure
  • ₹13100 - ₹100910.65
  • Product name: Fumagillin
  • CAS: 23110-15-8
  • MF: C26H34O7
  • MW: 458.54
  • EINECS:245-433-8
  • MDL Number:MFCD03990453
  • Synonyms:1-oxaspiro(2,5)oct-6-ylester ;2,4,6,8-decatetraenedioicacid,mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-buteny ;5beta,6beta(all-e)]]-theta ;6,8-decatetraenedioicacid,4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-4 ;amebacillin ;10-[[5-Methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-2-oxaspiro[2.5]oct-6-yl]oxy]-10-oxo-deca-2,4,6,8-tetraenoic acid;Fumagilin DCH;[3R-[3alpha,4alpha(2RX,3RX),5beta,6beta(all-E)]]-2,4,6,8-Decatetraenedioic acid, mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] ester
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 1ML
  • 500μG
  • ManufacturerSigma-Aldrich(India)
  • Product number344845
  • Product descriptionFumagillin, Aspergillus fumigatus - CAS 23110-15-8 - Calbiochem Antiprotozoal agent and angiogenesis inhibitor.
  • Packaging500μG
  • Price₹13100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF6771
  • Product descriptionFumagillin from Aspergillus fumigatus ≥90%, powder
  • Packaging1MG
  • Price₹27950.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number37017
  • Product descriptionFumagillin solution ~100?μg/mL in acetonitrile, analytical standard
  • Packaging1ML
  • Price₹54410.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF6771
  • Product descriptionFumagillin from Aspergillus fumigatus ≥90%, powder
  • Packaging5MG
  • Price₹100910.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 344845 Fumagillin, Aspergillus fumigatus - CAS 23110-15-8 - Calbiochem Antiprotozoal agent and angiogenesis inhibitor. 500μG ₹13100 2022-06-14 Buy
Sigma-Aldrich(India) F6771 Fumagillin from Aspergillus fumigatus ≥90%, powder 1MG ₹27950.15 2022-06-14 Buy
Sigma-Aldrich(India) 37017 Fumagillin solution ~100?μg/mL in acetonitrile, analytical standard 1ML ₹54410.3 2022-06-14 Buy
Sigma-Aldrich(India) F6771 Fumagillin from Aspergillus fumigatus ≥90%, powder 5MG ₹100910.65 2022-06-14 Buy

Properties

Melting point :194-195℃
alpha :D25 -26.6° (c = 1 in 95% ethanol)
Boiling point :484.03°C (rough estimate)
Density :1.1368 (rough estimate)
refractive index :1.5800 (estimate)
Flash point :2℃
storage temp. :2-8°C
solubility :ethanol: 1 mg/mL
form :powder
pka :4.27±0.10(Predicted)
color :white
Sensitive :Air Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :NGGMYCMLYOUNGM-ZILXAVPASA-N
LogP :3.260 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Fumagillin is an antibiotic derived from the fungus A. fumigatus. It binds and inhibits methionine aminopeptidase-2 with an IC50 value of 10 nM. Fumagillin inhibits angiogenesis by impairing the growth of endothelial cells and altering gene expression. It also impairs microsporidial replication and can be used to treat both conjunctival and intestinal microsporidial infections in immunocompromised patients. Finally, fumagillin reduces diet-induced adipose tissue formation in mice, independent of its effects on angiogenesis.

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
FUMAGILLIN
₹0.00 /25KG
FUMAGILLIN CAS:23110-15-8
Ouhuang Engineering Materials (Hubei) Co., Ltd
fumagillin
₹15.00 /1kg
fumagillin CAS:23110-15-8
Apeloa production Co.,Limited
fumagillin
₹1.00 /1g
fumagillin CAS:23110-15-8
Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates Clearsynth Labs CLEARSYNTH LABS LTD.
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED