Gemfibrozil
- ₹5260.95 - ₹32052.83
- Product name: Gemfibrozil
- CAS: 25812-30-0
- MF: C15H22O3
- MW: 250.33
- EINECS:247-280-2
- MDL Number:MFCD00079335
- Synonyms:PENTANOIC ACID, 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYL-;5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID;5-(2,5-DIMETHYL-PHENOXY)-2,2-DIMETHYL-PENTANOIC ACID;2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID;2,2-DIMETHYL-5-(2,5-XYLYLOXY) VALERIC ACID;GEMFIBROZIL;Gemcitabine intermediates;5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
6 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
Package
- 100MG
- 1G
- 5G
- 25G
- ManufacturerSigma-Aldrich(India)
- Product numberG9518
- Product descriptionGemfibrozil
- Packaging25G
- Price₹32052.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG9518
- Product descriptionGemfibrozil
- Packaging5G
- Price₹9666.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1286
- Product descriptionGemfibrozil Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹8107.93
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number91823
- Product descriptionGemfibrozil analytical standard
- Packaging100MG
- Price₹5260.95
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberG0368
- Product descriptionGemfibrozil min. 98.0 %
- Packaging25G
- Price₹9700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberG0368
- Product descriptionGemfibrozil min. 98.0 %
- Packaging5G
- Price₹6800
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | G9518 | Gemfibrozil | 25G | ₹32052.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G9518 | Gemfibrozil | 5G | ₹9666.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1286 | Gemfibrozil Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹8107.93 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 91823 | Gemfibrozil analytical standard | 100MG | ₹5260.95 | 2022-06-14 | Buy |
TCI Chemicals (India) | G0368 | Gemfibrozil min. 98.0 % | 25G | ₹9700 | 2022-05-26 | Buy |
TCI Chemicals (India) | G0368 | Gemfibrozil min. 98.0 % | 5G | ₹6800 | 2022-05-26 | Buy |
Properties
Melting point :61-63°C
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Gemfibrozil is a fibrate that activates peroxisome proliferator-activator α (PPARα, EC50 = 193 μM) with 100% efficacy. It also activates PPARγ (EC50 = 148 μM), but with only 79% efficacy. Presumably through its effects on PPARα, gemfibrozil lowers triglycerides and increases high density lipoprotein cholesterol levels and is used in the context of atherogenic dyslipidemia. Gemfibrozil strongly binds liver fatty acid-binding protein (Ki = 1.8 μM). Phase II metabolites of gemfibrozil inhibit certain cytochrome P450 isoforms, increasing drug-drug interaction risks.More related product prices
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