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geninthiocin

geninthiocin Structure
  • ₹0
  • Product name: geninthiocin
  • CAS: 158792-27-9
  • MF: C50H49N15O15S
  • MW: 1132.08
  • EINECS:
  • MDL Number:
  • Synonyms:geninthiocin;14-DeMethylberinaMycin;PubChem ID: 16129809;Geninthiocin A;Alaninamide, L-threonyl-2-[(1Z)-1-amino-1-propen-1-yl]-4-oxazolecarbonyl-2,3-didehydroalanyl-3-methyl-L-threonyl-2-(1-aminoethenyl)-5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-6-[2-(1-aminoethenyl)-4-oxazolyl]-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (7→1)-...
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Properties

Density :1.54±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble; DMSO: soluble; Ethanol: slightly soluble
form :White to off-white amorphous powder.
pka :10.01±0.60(Predicted)

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Geninthiocin A is a cyclic thiopeptide bacterial metabolite originally isolated from Streptomyces sp. DD84. It is active against a variety of Gram-positive bacteria (MICs = 0.2-4 μg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 μg/ml), and the fungus M. hiemalis (MIC = 38 μg/ml). Geninthiocin A also induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml.

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