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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Germacrone

Germacrone

Germacrone Structure
  • ₹5300 - ₹82085.98
  • Product name: Germacrone
  • CAS: 6902-91-6
  • MF: C15H22O
  • MW: 218.33
  • EINECS:
  • MDL Number:MFCD00210050
  • Synonyms:(E,E)-Germacra-3,7(11),9-trien-6-one;(E,E)-3,7-Dimethyl-10-(1-methylethylidene)-3,7-cyclodecadien-1-one;3,7-Dimethyl-10-(1-methylethylidene)-3,7-cyclodecadien-1-one;Germacra-3,7(11),9-trien-6-one, (E,E)-;trans,trans-3,7-Dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one;(3E,7E)-3,7-Dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one;GERMACRONE(RG);GERMACRONE
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 20MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberG0519
  • Product descriptionGermacrone min. 98.0 %
  • Packaging20MG
  • Price₹5300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0519
  • Product descriptionGermacrone min. 98.0 %
  • Packaging100MG
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number42924
  • Product descriptionGermacrone analytical standard
  • Packaging10MG
  • Price₹82085.98
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) G0519 Germacrone min. 98.0 % 20MG ₹5300 2022-05-26 Buy
TCI Chemicals (India) G0519 Germacrone min. 98.0 % 100MG ₹14800 2022-05-26 Buy
Sigma-Aldrich(India) 42924 Germacrone analytical standard 10MG ₹82085.98 2022-06-14 Buy

Properties

Melting point :55-58 °C
Boiling point :153-157 °C(Press: 13 Torr)
Density :0.9908 g/cm3
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
λmax :309nm(MeOH)(lit.)
BRN :2047453
Stability :Light Sensitive
LogP :4.760 (est)
CAS DataBase Reference :6902-91-6
NIST Chemistry Reference :3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (e,e)-(6902-91-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Germacrone is a sesquiterpene that has been found in gingeraceae plants and has diverse biological activities. It inhibits pseudorabies virus (PRV) replication in Vero cells when used at concentrations ranging from 10 to 150 μM. Germacrone (50-250 μM) enhances cytotoxicity and apoptosis induced by doxorubicin in doxorubicin-resistant MCF-7/adr cells. In vivo, germacrone (5, 10, and 20 mg/kg) reduces body weight gain, visceral fat pad weight, serum insulin and plasma glucose levels, and hepatic lipid levels in a mouse model of high-fat diet-induced obesity. It decreases brain malondialdehyde (MDA) levels and activity of superoxide dismutase (SOD) and glutathione peroxidase (GPX), as well as reduces infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).

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