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ChemicalBook > Product Catalogue >Natural Products >Terpenes >Ginkgolide B

Ginkgolide B

Ginkgolide B Structure
  • ₹5200 - ₹44198.48
  • Product name: Ginkgolide B
  • CAS: 15291-77-7
  • MF: C20H24O10
  • MW: 424.4
  • EINECS:604-876-0
  • MDL Number:MFCD05662347
  • Synonyms:7-DEOXYGINKGOLIDE C;BN 52021;GINKGOLIDE B;ginkgolide B from ginkgo leaves;(1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione;ginkgolide b from ginkgo biloba leaves;GinkgolideA,1-hydroxy-, (1β)-;Ginkgolide B, froM Ginkgo biloba
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10mg
  • 25MG
  • 50mg
  • 100MG
  • ManufacturerALFA India
  • Product numberALF-J60646-MA
  • Product descriptionGinkgolide B
  • Packaging10mg
  • Price₹6978
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J60646-MF
  • Product descriptionGinkgolide B
  • Packaging50mg
  • Price₹36668
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0553
  • Product descriptionGinkgolide B
  • Packaging25MG
  • Price₹5200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0553
  • Product descriptionGinkgolide B
  • Packaging100MG
  • Price₹11200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG6910
  • Product descriptionGinkgolide B from Ginkgo biloba leaves ≥90% (HPLC)
  • Packaging10MG
  • Price₹12708.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number94970
  • Product descriptionGinkgolide B analytical standard
  • Packaging10MG
  • Price₹17817.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG6910
  • Product descriptionGinkgolide B from Ginkgo biloba leaves ≥90% (HPLC)
  • Packaging50MG
  • Price₹44198.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J60646-MA Ginkgolide B 10mg ₹6978 2022-05-26 Buy
ALFA India ALF-J60646-MF Ginkgolide B 50mg ₹36668 2022-05-26 Buy
TCI Chemicals (India) G0553 Ginkgolide B 25MG ₹5200 2022-05-26 Buy
TCI Chemicals (India) G0553 Ginkgolide B 100MG ₹11200 2022-05-26 Buy
Sigma-Aldrich(India) G6910 Ginkgolide B from Ginkgo biloba leaves ≥90% (HPLC) 10MG ₹12708.55 2022-06-14 Buy
Sigma-Aldrich(India) 94970 Ginkgolide B analytical standard 10MG ₹17817.95 2022-06-14 Buy
Sigma-Aldrich(India) G6910 Ginkgolide B from Ginkgo biloba leaves ≥90% (HPLC) 50MG ₹44198.48 2022-06-14 Buy

Properties

Melting point :280°C (dec.)
alpha :D24 -52.6° (c = 1 in ethanol)
Boiling point :762.4±60.0 °C(Predicted)
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 10 mg/ml).
pka :pKa1 7.14; pKa2 8.60; pKa3 11.89(at 25℃)
form :Solid
color :White
Water Solubility :Soluble in DMSO. Slightly soluble in water and ethanol
BRN :4727611
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :SQOJOAFXDQDRGF-MMQTXUMRSA-N
SMILES :[C@@]12(O)[C@]34C(=O)O[C@@H]5C[C@@H](C(C)(C)C)C6([C@@H](O)C(=O)O[C@@]6([H])O3)C45[C@H](O)[C@]1([H])OC(=O)[C@H]2C
LogP :2.070 (est)
CAS DataBase Reference :15291-77-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Platelet-activating factor (PAF) is an important mediator of cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation. These cellular effects are mediated through its specific G-protein coupled receptor, PAFR. Ginkgolide B, a terpenoid extracted from G. biloba leaves, is a potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 μM. It has been shown to inhibit non-mucinous ovarian cancer proliferation by blocking cell cycling. Ginkgolide B also demonstrates number of other anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects.

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