JASPLAKINOLIDE
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- ₹78708.58
- Product name: JASPLAKINOLIDE
- CAS: 102396-24-7
- MF: C36H45BrN4O6
- MW: 709.67
- EINECS:
- MDL Number:MFCD00873735
- Synonyms:JASPLAKINOLIDE;JASPLAKINOLIDE, JASPIS JOHNSTONI;(3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone;[3S,6R,9R,13S,15R,19S,16E,(+)]-6-[(2-Bromo-1H-indol-3-yl)methyl]-9-(4-hydroxyphenyl)-3,5,13,15,17,19-hexamethyl-2,5,8-triaza-12-oxacyclononadecan-16-ene-1,4,7,11-tetrone;NSC 613009;Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem;Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl];GQWYWHOHRVVHAP-DHKPLNAMSA-N
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 100μG
- ManufacturerSigma-Aldrich(India)
- Product numberJ4580
- Product descriptionJasplakinolide ≥97% (HPLC)
- Packaging100μG
- Price₹78708.58
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | J4580 | Jasplakinolide ≥97% (HPLC) | 100μG | ₹78708.58 | 2022-06-14 | Buy |
Properties
Melting point :110℃ (decomposition)
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige
Safety Information
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Description
Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in vitro but disrupts actin filaments and induces irregular polymerization of monomeric actin in vivo. This compound is used to investigate the role of actin in diverse cellular roles, such as motility, transport, and development.More related product prices
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