L-AP4
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- ₹5569 - ₹30483.2
- Product name: L-AP4
- CAS: 23052-81-5
- MF: C4H10NO5P
- MW: 183.1
- EINECS:200-258-5
- MDL Number:MFCD00083244
- Synonyms:L-AP4;L(+)-2-AMINO-4-PHOSPHONOBUTANOIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID;L-(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4);L(+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID 97%;(2S)-2-Amino-4-phosphonobutyric acid;(S)-4-Phosphono-2-aminobutanoic acid;(S)-4-Phosphono-2-aminobutyric acid
6 prices
Selected condition：
Brand
- ALFA India
- Sigma-Aldrich(India)
Package
- 1mg
- 50μG
- 0.5MG
- 10mg
- ManufacturerALFA India
- Product numberALF-J64075-MCR
- Product description(S)-(+)-2-Amino-4-phosphonobutyric acid, 97%
- Packaging1mg
- Price₹5569
- Updated2022-05-26
- Buy
- ManufacturerALFA India
- Product numberALF-J64075-MA
- Product description(S)-(+)-2-Amino-4-phosphonobutyric acid, 97%
- Packaging10mg
- Price₹29369
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA7929
- Product descriptionL-(+)-2-Amino-4-phosphonobutyric acid optical purity optical purity: ≥95% (HPLC, Marfey′s reagent)
- Packaging0.5MG
- Price₹8440
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number165300
- Product descriptionL-(+)-2-Amino-4-phosphonobutyric Acid - CAS 23052-81-5 - Calbiochem
- Packaging1MG
- Price₹10550.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA7929
- Product descriptionL-(+)-2-Amino-4-phosphonobutyric acid optical purity optical purity: ≥95% (HPLC, Marfey′s reagent)
- Packaging1MG
- Price₹14020
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSRP4667
- Product descriptionGDF-5 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
- Packaging50μG
- Price₹30483.2
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ALFA India | ALF-J64075-MCR | (S)-(+)-2-Amino-4-phosphonobutyric acid, 97% | 1mg | ₹5569 | 2022-05-26 | Buy |
| ALFA India | ALF-J64075-MA | (S)-(+)-2-Amino-4-phosphonobutyric acid, 97% | 10mg | ₹29369 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | A7929 | L-(+)-2-Amino-4-phosphonobutyric acid optical purity optical purity: ≥95% (HPLC, Marfey′s reagent) | 0.5MG | ₹8440 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 165300 | L-(+)-2-Amino-4-phosphonobutyric Acid - CAS 23052-81-5 - Calbiochem | 1MG | ₹10550.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A7929 | L-(+)-2-Amino-4-phosphonobutyric acid optical purity optical purity: ≥95% (HPLC, Marfey′s reagent) | 1MG | ₹14020 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SRP4667 | GDF-5 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC) | 50μG | ₹30483.2 | 2022-06-14 | Buy |
Properties
Melting point :207-215 °C
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)
Boiling point :491.7±55.0 °C(Predicted)
Density :1.628±0.06 g/cm3(Predicted)
storage temp. :0-6°C
solubility :H2O : 50 mg/mL (273.07 mM; Need ultrasonic)
pka :2.19±0.10(Predicted)
form :solid
color :White
Water Solubility :Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
Sensitive :Light Sensitive
CAS DataBase Reference :23052-81-5(CAS DataBase Reference)
Safety Information
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Description
Metabotropic glutamate receptors (mGluR) function to modulate excitatory synaptic transmission in the brain. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7, and 8) inhibit adenylyl cyclase. L-AP4, an analog of L-glutamic acid, is a selective Group III mGluR agonist that functions presynaptically to suppress glutamate release (IC50 = 2.5 μM). L-AP4 has been shown to depress synaptic transmission in glutamatergic pathways in the hippocampus, olfactory bulb, and retina as well as act as an agonist at the quisqualate-sensitized AP6 site in hippocampus.More related product prices
(S)-2-Amino-2-methyl-4-phosphonobutanoic acid 20263-07-4 1,2-Diaminopropane L-AP4Related product price
- 20263-07-4
₹15650-82780 - 13138-33-5
₹15371.5 - 4-PHOSPHONOBUTYRIC ACID
₹3700-10800
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