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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Thyroid hormone and antithyroid drugs >L-Thyroxine

L-Thyroxine

L-Thyroxine Structure
  • ₹3009.35 - ₹41903.58
  • Product name: L-Thyroxine
  • CAS: 51-48-9
  • MF: C15H11I4NO4
  • MW: 776.87
  • EINECS:200-101-1
  • MDL Number:MFCD00002596
  • Synonyms:3,5,3’,5’-tetraiodothyronine ;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine ;l-3,5,3’,5’-tetraiodothyronine ;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin ;β-((3,5-Diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl)alanine ;3,5,3',5'-TETRAIODO-L-THYRONINE;3,3',5,5'-TETRAIODO-L-THYRONIN;3,3',5,5'-TETRAIODO-L-THYRONINE
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 1ML
  • 1G
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2376
  • Product descriptionL-Thyroxine ≥98% (HPLC)
  • Packaging5G
  • Price₹41903.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1775
  • Product descriptionL-Thyroxine powder, BioReagent, suitable for cell culture
  • Packaging1G
  • Price₹14657.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2376
  • Product descriptionL-Thyroxine ≥98% (HPLC)
  • Packaging1G
  • Price₹11745.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT-073
  • Product descriptionL-Thyroxine (T4) solution 100?μg/mL in methanol with 0.1N NH3, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹9482.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1613
  • Product descriptionLevothyroxine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9103.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1775
  • Product descriptionL-Thyroxine powder, BioReagent, suitable for cell culture
  • Packaging500MG
  • Price₹8465.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2376
  • Product descriptionL-Thyroxine ≥98% (HPLC)
  • Packaging500MG
  • Price₹8367.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT1775
  • Product descriptionL-Thyroxine powder, BioReagent, suitable for cell culture
  • Packaging100MG
  • Price₹3128.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2376
  • Product descriptionL-Thyroxine ≥98% (HPLC)
  • Packaging100MG
  • Price₹3009.35
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T2376 L-Thyroxine ≥98% (HPLC) 5G ₹41903.58 2022-06-14 Buy
Sigma-Aldrich(India) T1775 L-Thyroxine powder, BioReagent, suitable for cell culture 1G ₹14657.05 2022-06-14 Buy
Sigma-Aldrich(India) T2376 L-Thyroxine ≥98% (HPLC) 1G ₹11745.13 2022-06-14 Buy
Sigma-Aldrich(India) T-073 L-Thyroxine (T4) solution 100?μg/mL in methanol with 0.1N NH3, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹9482.9 2022-06-14 Buy
Sigma-Aldrich(India) PHR1613 Levothyroxine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9103.83 2022-06-14 Buy
Sigma-Aldrich(India) T1775 L-Thyroxine powder, BioReagent, suitable for cell culture 500MG ₹8465.15 2022-06-14 Buy
Sigma-Aldrich(India) T2376 L-Thyroxine ≥98% (HPLC) 500MG ₹8367.73 2022-06-14 Buy
Sigma-Aldrich(India) T1775 L-Thyroxine powder, BioReagent, suitable for cell culture 100MG ₹3128.43 2022-06-14 Buy
Sigma-Aldrich(India) T2376 L-Thyroxine ≥98% (HPLC) 100MG ₹3009.35 2022-06-14 Buy

Properties

Melting point :235 °C
alpha :-5 º (1N NaOH:EtOH 1:2)
Density :2.4440 (estimate)
Flash point :9℃
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Dissolves in 4M ammonium hydroxide in Methanol at 50mg/ml
pka :2.2(at 25℃)
form :Powder
Boiling point :576.3±50.0 °C(Predicted)
color :White to Pale Brown
optical activity :-4.5 to -5.7 [1 mol dm-3 NaOH-ethanol (1:2)] +15 [1 mol dm-3 HCl-95% ethanol (1:2)]
Water Solubility :insoluble
Sensitive :Light Sensitive
Merck :9491
BRN :2228515
InChIKey :XUIIKFGFIJCVMT-LBPRGKRZSA-N
CAS DataBase Reference :51-48-9(CAS DataBase Reference)
EPA Substance Registry System :L-Thyroxine (51-48-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378 In case of fire: Use … for extinction.

Description

Thyroxine (T4) is a thyroid hormone that impacts diverse developmental and physiological processes in vertebrates. L-T4 is a synthetic form of the natural hormone. It is used to treat hypothyroidism but is known to cause various side effects, including hypothyroidism upon withdrawal.

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