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laudanosine

laudanosine  Structure
  • ₹0
  • Product name: laudanosine
  • CAS: 2688-77-9
  • MF: C21H27NO4
  • MW: 357.44
  • EINECS:220-253-2
  • MDL Number:MFCD27978049
  • Synonyms:Nsc 35045;(+)-(S)-Laudanosine;(1S)-1,2,3,4-Tetrahydro-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline;[1S,(+)]-1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline;Einecs 220-253-2;Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1S)-;(S)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline;Cisatracurium Besylate Impurity 49
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :89°
alpha :D16 +106° (c = 1.6 in 97% alc); D16 +130° (chloroform); D22 +52.2 ±1.3° (chloroform); D20 +82.5° (ethanol)
Boiling point :490.07°C (rough estimate)
Density :1.1729 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly, Sonicated)
form :White to Pale Beige
pka :7.80±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.

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