Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook > Product Catalogue >API >Nervous system drugs >Antiparkinson Drugs >Levodopa

Levodopa

Levodopa Structure
  • ₹387 - ₹125321.03
  • Product name: Levodopa
  • CAS: 59-92-7
  • MF: C9H11NO4
  • MW: 197.19
  • EINECS:200-445-2
  • MDL Number:MFCD00002598
  • Synonyms:3,4-Dihydroxyphenyl-L-alanine;3,4-L-DIHYDROXYPHENYLALANINE;BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE;HYDROXYTYROSINE;H-PHE(3,4-DI-HYDROXY)-OH;H-PHE(3,4-DI-OH)-OH;H-TYR(3-HYDROXY)-OH;L-BETA-(3,4-DIHYDROXYPHENYL)ALANINE
14 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

Package

  • 50MG
  • 500MG
  • 1gm
  • 5G
  • 5gm
  • 25gm
  • 25G
  • 100G
  • 500G
  • 5Gms
  • 25Gms
  • ManufacturerTCI Chemicals (India)
  • Product numberD0600
  • Product description3-(3,4-Dihydroxyphenyl)-L-alanine
  • Packaging5G
  • Price₹2300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0600
  • Product description3-(3,4-Dihydroxyphenyl)-L-alanine
  • Packaging25G
  • Price₹6200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0600
  • Product description3-(3,4-Dihydroxyphenyl)-L-alanine
  • Packaging100G
  • Price₹16100
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9628
  • Product description3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)
  • Packaging5G
  • Price₹3637.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1271
  • Product descriptionLevodopa Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹9818.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9628
  • Product description3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)
  • Packaging25G
  • Price₹12557
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number72816
  • Product description3,4-Dihydroxy-L-phenylalanine certified reference material, TraceCERT?
  • Packaging50MG
  • Price₹12730.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9628
  • Product description3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)
  • Packaging100G
  • Price₹36140
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9628
  • Product description3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)
  • Packaging500G
  • Price₹125321.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number77201
  • Product descriptionL-Dopa extrapure, 99%
  • Packaging5Gms
  • Price₹930
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number77201
  • Product descriptionL-Dopa extrapure, 99%
  • Packaging25Gms
  • Price₹4210
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 2446
  • Product descriptionL-Dopa, 99% 99%+
  • Packaging1gm
  • Price₹387
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 2446
  • Product descriptionL-Dopa, 99% 99%+
  • Packaging5gm
  • Price₹873
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 2446
  • Product descriptionL-Dopa, 99% 99%+
  • Packaging25gm
  • Price₹3996
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D0600 3-(3,4-Dihydroxyphenyl)-L-alanine 5G ₹2300 2022-05-26 Buy
TCI Chemicals (India) D0600 3-(3,4-Dihydroxyphenyl)-L-alanine 25G ₹6200 2022-05-26 Buy
TCI Chemicals (India) D0600 3-(3,4-Dihydroxyphenyl)-L-alanine 100G ₹16100 2022-05-26 Buy
Sigma-Aldrich(India) D9628 3,4-Dihydroxy-L-phenylalanine ≥98% (TLC) 5G ₹3637.2 2022-06-14 Buy
Sigma-Aldrich(India) PHR1271 Levodopa Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹9818.28 2022-06-14 Buy
Sigma-Aldrich(India) D9628 3,4-Dihydroxy-L-phenylalanine ≥98% (TLC) 25G ₹12557 2022-06-14 Buy
Sigma-Aldrich(India) 72816 3,4-Dihydroxy-L-phenylalanine certified reference material, TraceCERT? 50MG ₹12730.2 2022-06-14 Buy
Sigma-Aldrich(India) D9628 3,4-Dihydroxy-L-phenylalanine ≥98% (TLC) 100G ₹36140 2022-06-14 Buy
Sigma-Aldrich(India) D9628 3,4-Dihydroxy-L-phenylalanine ≥98% (TLC) 500G ₹125321.03 2022-06-14 Buy
SRL 77201 L-Dopa extrapure, 99% 5Gms ₹930 2022-05-26 Buy
SRL 77201 L-Dopa extrapure, 99% 25Gms ₹4210 2022-05-26 Buy
ottokemi D 2446 L-Dopa, 99% 99%+ 1gm ₹387 2022-05-26 Buy
ottokemi D 2446 L-Dopa, 99% 99%+ 5gm ₹873 2022-05-26 Buy
ottokemi D 2446 L-Dopa, 99% 99%+ 25gm ₹3996 2022-05-26 Buy

Properties

Melting point :276-278 °C (lit.)
Boiling point :334.28°C (rough estimate)
alpha :-11.7 º (c=5.3, 1N HCl)
Density :1.3075 (rough estimate)
refractive index :-12 ° (C=5, 1mol/L HCl)
storage temp. :2-8°C
solubility :Slightly soluble in water, practically insoluble in ethanol (96 per cent). It is freely soluble in 1 M hydrochloric acid and sparingly soluble in 0.1 M hydrochloric acid .
pka :2.32(at 25℃)
form :Crystalline Powder
color :White to creamy
Odor :at 100.00 %. odorless
Odor Type :odorless
optical activity :-39.5 (H2O) -12.025 (1 mol dm-3 HCl)
Water Solubility :Slightly soluble in water, dilute hydrochloric acid and formic acid. Insoluble in ethanol.
Merck :14,5464
BRN :2215169
Stability :Stable. Incompatible with strong oxidizing agents. Light and air sensitive.
InChIKey :WTDRDQBEARUVNC-LURJTMIESA-N
LogP :-1.154 (est)
CAS DataBase Reference :59-92-7(CAS DataBase Reference)
NIST Chemistry Reference :Levodopa(59-92-7)
EPA Substance Registry System :Levodopa (59-92-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dopamine is a neurotransmitter involved in synaptic plasticity, cognition, and the regulation of locomotor control. It is produced endogenously in the substantia nigra and ventral tegmental area but when administered exogenously cannot cross the blood brain barrier. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier. It is produced from L-tyrosine by trysosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. It is conventionally used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery. However L-DOPA has a short half-life and is known to elevate homocysteine concentrations in plasma, which can be neurotoxic and induce oxidative damage.

Related product price