Levosimendan
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- ₹6200 - ₹34401.85
- Product name: Levosimendan
- CAS: 141505-33-1
- MF: C14H12N6O
- MW: 280.28
- EINECS:663-528-6
- MDL Number:MFCD00867135
- Synonyms:LEVOSIMENDAN;-2-[[4-(1，4，5，6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)19henyl]hydrazono]Propandinitrile;(R)-Simendan;[[4-[(4R)-1,4,5,6-Terahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]propanedinitrile;OR-1259;Simda;Mesoxalonitrile (-)-{p-[(R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl}hydrazone;(R)-2-[[4-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PHENYL] HYDROZONO]PRO
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 250MG
- ManufacturerTCI Chemicals (India)
- Product numberL0320
- Product descriptionLevosimendan
- Packaging50MG
- Price₹6200
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0320
- Product descriptionLevosimendan
- Packaging250MG
- Price₹17800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL5545
- Product descriptionLevosimendan ≥98% (HPLC)
- Packaging10MG
- Price₹8540.93
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL5545
- Product descriptionLevosimendan ≥98% (HPLC)
- Packaging50MG
- Price₹34401.85
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | L0320 | Levosimendan | 50MG | ₹6200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | L0320 | Levosimendan | 250MG | ₹17800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | L5545 | Levosimendan ≥98% (HPLC) | 10MG | ₹8540.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L5545 | Levosimendan ≥98% (HPLC) | 50MG | ₹34401.85 | 2022-06-14 | Buy |
Properties
Melting point :216-219°C (dec.)
alpha :D25 -566° (tetrahydrofurane/methanol)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
pka :6.3(at 25℃)
form :powder
color :yellow
optical activity :[α]/D -500 to -650°, c = 0.5 in THF
alpha :D25 -566° (tetrahydrofurane/methanol)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
pka :6.3(at 25℃)
form :powder
color :yellow
optical activity :[α]/D -500 to -650°, c = 0.5 in THF
Safety Information
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Description
Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C (EC50 = 9 nM), promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells (EC50 = 0.28 μM), and performs a cardioprotective function by prompting the opening of mitochondrial potassium channels in cardiomyocytes. It also has been reported to inhibit phosphodiesterases 3 and 4 in left ventricular cardiac tissue with IC50 values of 2.5 nM and 25 μM, respectively.More related product prices
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₹7869.78
