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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >LIQUIRITIGENIN

LIQUIRITIGENIN

LIQUIRITIGENIN Structure
  • ₹12621.95 - ₹40561.28
  • Product name: LIQUIRITIGENIN
  • CAS: 578-86-9
  • MF: C15H12O4
  • MW: 256.25
  • EINECS:
  • MDL Number:MFCD00287289
  • Synonyms:7,4''-DIHYDROXYFLAVANONE hplc;(2S)-2α-(4-Hydroxyphenyl)-7-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one;(2S)-2α-(4-Hydroxyphenyl)-7-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one;(S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;(S)-7-Hydroxy-2-(p-hydroxyphenyl)chroman-4-one;(2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (2S)-;Aids095895
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product number78825
  • Product descriptionLiquiritigenin ≥97.0% (HPLC)
  • Packaging10MG
  • Price₹12621.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number78825
  • Product descriptionLiquiritigenin ≥97.0% (HPLC)
  • Packaging50MG
  • Price₹40561.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 78825 Liquiritigenin ≥97.0% (HPLC) 10MG ₹12621.95 2022-06-14 Buy
Sigma-Aldrich(India) 78825 Liquiritigenin ≥97.0% (HPLC) 50MG ₹40561.28 2022-06-14 Buy

Properties

Melting point :206-208°C
Boiling point :529.5±50.0 °C(Predicted)
Density :1.386±0.06 g/cm3(Predicted)
Flash point :207℃
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO : 125 mg/mL (487.80 mM; Need ultrasonic)
form :powder
pka :7.71±0.40(Predicted)
color :White
BRN :359378
InChIKey :FURUXTVZLHCCNA-AWEZNQCLSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Liquiritigenin is an active estrogenic component in extracts of Glycyrrhizae radix. Glycyrrhizae radix (G. radix, licorice, liquorice) is frequently used for life-enhancing properties, for the treatment of injury or swelling, for detoxification in traditional Oriental medicine, as well as a food supplement in many of the countries in the world.  Liquiritigenin is a selective estrogen receptor-β (ERβ) agonist.  Liquiritigenin activates multiple ER regulatory elements and native target genes with ERβ but not ERα. The ERβ-selectivity of liquiritigenin is due to the selective recruitment of the coactivator steroid receptor coactivator-2 to target genes.
As the targeting ERβ is associated with anti-inflammatory effects, liquiritigenin exerts anti-inflammatory effects. Liquiritigenin is also reported to antihyperlipidemic, antiallergic and antihepatocellular carcinoma effects.

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