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MIBEFRADIL

MIBEFRADIL Structure
  • ₹13975.08 - ₹55824.53
  • Product name: MIBEFRADIL
  • CAS: 116666-63-8
  • MF: C29H40Cl2FN3O3
  • MW: 568.5506032
  • EINECS:
  • MDL Number:MFCD11044451
  • Synonyms:[(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methyl-amino]ethyl]-6-fluoro-1-isopropyl-tetralin-2-yl] 2-methoxyacetate dihydrochloride;MIBEFRADIL;Mibefradil diHCl;(1S,2S)-2-[2[[3-(2-Benzimidazolyl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride hydrate;(1s-cis)-orid ;2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-aceticaci ;6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenylester,dihydrochl ;ro40-5967/001
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5441
  • Product descriptionMibefradil dihydrochloride hydrate ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹13975.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM5441
  • Product descriptionMibefradil dihydrochloride hydrate ≥98% (HPLC), powder
  • Packaging25MG
  • Price₹55824.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M5441 Mibefradil dihydrochloride hydrate ≥98% (HPLC), powder 5MG ₹13975.08 2022-06-14 Buy
Sigma-Aldrich(India) M5441 Mibefradil dihydrochloride hydrate ≥98% (HPLC), powder 25MG ₹55824.53 2022-06-14 Buy

Properties

Melting point :128℃
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :H2O: 24 mg/mL, soluble
pka :4.8; 5.5(at 25℃)
form :solid
color :white
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 μM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use as an anti-hypertensive agent.

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