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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >Terfenadine

Terfenadine

Terfenadine Structure
  • ₹10857.48 - ₹42867
  • Product name: Terfenadine
  • CAS: 50679-08-8
  • MF: C32H41NO2
  • MW: 471.67
  • EINECS:256-710-8
  • MDL Number:MFCD00079622
  • Synonyms:TERFENADINE;a-[4-(1,1-Dmethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol;A1lerplus;Triludma;ALPHA-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINEBUTANOL;1-(p-tert-Butylphenyl)-4-(4'-(alpha-hydroxydiphenylmethyl)-1'-piperidyl)-butanol;(R)-α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidine-1-butanol;[R,(+)]-α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidine-1-butanol
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5G
  • 25G
  • ManufacturerSigma-Aldrich(India)
  • Product numberT9652
  • Product descriptionTerfenadine
  • Packaging5G
  • Price₹10857.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT9652
  • Product descriptionTerfenadine
  • Packaging25G
  • Price₹42867
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T9652 Terfenadine 5G ₹10857.48 2022-06-14 Buy
Sigma-Aldrich(India) T9652 Terfenadine 25G ₹42867 2022-06-14 Buy

Properties

Melting point :145-152 °C
Boiling point :572.76°C (rough estimate)
Density :1.0488 (rough estimate)
refractive index :1.6310 (estimate)
storage temp. :2-8°C
solubility :chloroform: soluble250 mg plus 5 ml of solvent, clear to very slightly hazy, colorless to faintly yellow
form :Solid
pka :pKa 9.21(H2O t = 25 I = 0.025) (Uncertain)
color :White to Off-White
Water Solubility :0.001 g/100 mL (30 ºC)
CAS DataBase Reference :50679-08-8(CAS DataBase Reference)
NIST Chemistry Reference :Seldane(50679-08-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Terfenadine has been used to study the role of histamine in itch related to proteinase-activated receptors (PARs) in mice. Terfenadine has also been used to block histamine receptor type 1 to study the pathogenesis of 2,4-dinitrobenzene sulfonic acid (DNBS)-induced ulcerative colitis in rats.

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1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol CAS:50679-08-8
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