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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >Fexofenadine

Fexofenadine

Fexofenadine Structure
  • ₹0
  • Product name: Fexofenadine
  • CAS: 83799-24-0
  • MF: C32H39NO4
  • MW: 501.66
  • EINECS:801-893-7
  • MDL Number:MFCD00871892
  • Synonyms:TERFENADINECARBOXYLATE;alpha-dimethyl-tyl)-alph ;benzeneaceticacid,4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)bu ;mdl16455 ;terfenadineacidmetabolite ;2-(4-(1-HYDROXY-4-[4-(HYDROXY-DIPHENYL-METHYL)-PIPERIDIN-1-YL]-BUTYL)-PHENYL)-2-METHYL-PROPIONIC ACID;Fexofenadinebase;FEXOFENADINE(SUBJECTTOPATENTFREE)
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :218-220°C
Boiling point :697.3±55.0 °C(Predicted)
Density :1.171±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Methanol (Slightly, Heated, Sonicated)
form :Solid
pka :4.43±0.10(Predicted)
color :White to Off-White
BCS Class :1,3
LogP :2.81
CAS DataBase Reference :83799-24-0(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Fexofenadine, the carboxylic acid metabolite of terfenadine, is widely available. It accounts for the antihistaminic properties of terfenadine, which is very rapidly metabolized via CYP3A4-catalyzed processes. Members of the organic anion transporter protein family and the drug efflux transporter P-glycoprotein are involved in the disposition of fexofenadine. Fexofenadine does not have the antiarrhythmic side effects of terfenadine.

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