Fexofenadine
- CAS No.
- 83799-24-0
- Chemical Name:
- Fexofenadine
- Synonyms
- Carnipure tartrate;FEX-12;mdl16455;FEXOFENADINE;Fexafenadine;Fexofenadine-D5;Fexofenadinebase;Terfenadine acid;Fexofenadine API;MDL-16455：Allegra
- CBNumber:
- CB5473513
- Molecular Formula:
- C32H39NO4
- Molecular Weight:
- 501.66
- MOL File:
- 83799-24-0.mol
- Modify Date:
- 2023/10/8 13:01:37
| Melting point | 218-220°C |
|---|---|
| Boiling point | 697.3±55.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Methanol (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 4.43±0.10(Predicted) |
| color | White to Off-White |
| BCS Class | 1,3 |
| LogP | 2.81 |
| CAS DataBase Reference | 83799-24-0(CAS DataBase Reference) |
Fexofenadine Chemical Properties,Uses,Production
Description
Fexofenadine, the carboxylic acid metabolite of terfenadine, is widely available. It accounts for the antihistaminic properties of terfenadine, which is very rapidly metabolized via CYP3A4-catalyzed processes. Members of the organic anion transporter protein family and the drug efflux transporter P-glycoprotein are involved in the disposition of fexofenadine. Fexofenadine does not have the antiarrhythmic side effects of terfenadine.
Chemical Properties
White Powder
Uses
A metabolite of of terfenadine, a H1-Histamine receptor antagonist
Definition
ChEBI: A piperidine-based anti-histamine compound.
Fexofenadine Preparation Products And Raw materials
Raw materials
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Global( 213)Suppliers
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|---|---|---|---|---|---|
| AVD pharmaceuticals Pvt Ltd | +919860835260 | Pune, India | 102 | 58 | Inquiry |
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83799-24-0(Fexofenadine)Related Search:
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TERFENADINECARBOXYLATE
alpha-dimethyl-tyl)-alph
benzeneaceticacid,4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)bu
mdl16455
terfenadineacidmetabolite
2-(4-(1-HYDROXY-4-[4-(HYDROXY-DIPHENYL-METHYL)-PIPERIDIN-1-YL]-BUTYL)-PHENYL)-2-METHYL-PROPIONIC ACID
Fexofenadinebase
FEXOFENADINE(SUBJECTTOPATENTFREE)
2-[4-[1-hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]butyl]phenyl]-2-methyl-propanoic acid
α, α-Dimethyl-4-[l-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]benz
4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylphenylacetic acid
Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-
4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
CARBOXYTERFENADINE
FEXOFENADINE
terfenidine carboxylate
MDL-16455：Allegra
Fexafenadine
2-[4-[1-Hydroxy-4-[4-(α-hydroxybenzhydryl)piperidine-1-yl]butyl]phenyl]-2-methylpropanoic acid
Terfenadine acid
Terfenadine caroxylate
α,α-Dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidino]butyl]benzeneacetic acid
Fexafenadine Hydrochloride
2-[4-[1-hydroxy-4-[4-[hydroxy-di(phenyl)methyl]-1-piperidyl]butyl]phenyl]-2-methyl-propionic acid
2-[4-[1-hydroxy-4-[4-[hydroxy-di(phenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid
2-[4-[1-hydroxy-4-[4-[hydroxy-di(phenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methyl-propanoic acid
Fexofenadine Hydroch
Fexofenadine-D5
4-[1-Hydroxy-4-[4-(hydroxydiphenylMethyl)-1-piperidinyl]butyl]-α,α-diMethyl-benzene-acetic Acid
2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-piperidin-1-yl)butyl)phenyl)-2-methylpropanoic ac
FEX-12
α, α-Dimethyl -4- [ 1-hydroxy-4- [ 4-
(hydroxydiphenylmethyl) -1- piperidinyl ] butyl
] Benzene acetic acid (Fexofenadine Base)
Methyl 4-[4-[4-(Hydroxy Diphenyl Methyl)-1-Piperidinyl]-1-Oxobutyl]-A,A-Dimethyl Phenylacetate
2-(4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid (Fexofenadine Base)
2-[4-[(1S)-1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]butyl]phenyl]-2-methylpropanoic acid
Fexofenadine (200 mg) (2-(4-{1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid dihydrate)
Benzeneacetic acid,4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethyl-
Fexofenadine USP/EP/BP
Fexofenadine (10mM in DMSO)
Fexofenadine HCL- IP/EP/USP
Fexofenadine API
Carboxyterfenadine-D3
TIANU-CHEM_Fexofenadine 83799-24-0
Carnipure tartrate
4-[4-[4-hydroxydiphenylmethyl]-1-piperidinyl]-1-hydroxybutyl]-a,adimethylbenzeneacetic acid
Fexofenadine Hcl EP/USP/JP
Fexofenadine
(R)-2-(4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1- yl)butyl)phenyl)-2-methylpropanoic acid
4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethyl-benzene-aceticAcid (Fexofenadine Base
83799-24-0
754477-55-1
C32H39NO4
API
Histamine receptor
Aromatics
Heterocycles
Metabolites & Impurities
Intermediates & Fine Chemicals
Metabolites