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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pituitary hormone drugs >MK-677

MK-677

MK-677 Structure
  • ₹14516.33 - ₹57870.45
  • Product name: MK-677
  • CAS: 159752-10-0
  • MF: C28H40N4O8S2
  • MW: 624.77
  • EINECS:1308068-626-2
  • MDL Number:MFCD00942284
  • Synonyms:2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate;(R)-1'-(2-Methylalanyl-O-benzyl-D-seryl)-1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] Mesylate;Crescendo;IbutaMoren Mesylate(MK-677);MK-667;N-[1(R)-1,2-Dihydro-1-methanesulfonylspiro-3H-indole-3,4′-piperidin)-1′-yl]carbonyl-2-(phenylmethoxy)-ethyl-2-amino-2-methylpropanamide methanesulfonate;MK-677(Ibutamoren);Ibutamoren, MK-0677
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0993
  • Product descriptionMK-677 ≥98% (HPLC)
  • Packaging5MG
  • Price₹14516.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0993
  • Product descriptionMK-677 ≥98% (HPLC)
  • Packaging25MG
  • Price₹57870.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0993 MK-677 ≥98% (HPLC) 5MG ₹14516.33 2022-06-14 Buy
Sigma-Aldrich(India) SML0993 MK-677 ≥98% (HPLC) 25MG ₹57870.45 2022-06-14 Buy

Properties

Melting point :164-170°C
storage temp. :2-8°C
solubility :H2O: soluble5mg/mL, clear
form :powder
color :white to beige
InChIKey :DUGMCDWNXXFHDE-VZYDHVRKSA-N
SMILES :S(O)(=O)(=O)C.S(N1C2C=CC=CC=2C2(CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC3C=CC=CC=3)CC2)C1)(=O)(=O)C |&1:19,r|

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ghrelin is an endogenous ligand for the growth hormone (GH) secretagogue receptor (GHSR). Ibutamoren is an orally-active, non-peptidic agonist of GHSR (Kd = 0.4 nM) and, as a result, is a GH secretagogue. It elevates GH in dogs after oral doses as low as 0.125 mg/kg, without significantly changing plasma levels of aldosterone, luteinizing hormone, thyroxine, or prolactin.

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