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ChemicalBook > Product Catalogue >Organic Chemistry >Carboxylic acids and derivatives >Carboxylic acid esters and derivatives >Monoethyl fumarate

Monoethyl fumarate

Monoethyl fumarate Structure
  • ₹3658.85 - ₹48000
  • Product name: Monoethyl fumarate
  • CAS: 2459-05-4
  • MF: C6H8O4
  • MW: 144.13
  • EINECS:219-544-7
  • MDL Number:MFCD00002699
  • Synonyms:(2E)-4-Ethoxy-4-oxo-2-butenoic acid;2-Butenedioic acid (E)-, monoethyl ester;Mono-Ethyl fuMarate 95%;Mono-Ethyl FuMarate, 97+%;(2E)-2-Butenedioic Acid Monoethyl Ester;FuMaric Acid Ethyl Ester;Monoethyl FuMerate;Monoethyl trans-2-Butenedioate
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 25G
  • 250G
  • ManufacturerTCI Chemicals (India)
  • Product numberF0359
  • Product descriptionMonoethyl Fumarate min. 97.0 %
  • Packaging25G
  • Price₹7600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF0359
  • Product descriptionMonoethyl Fumarate min. 97.0 %
  • Packaging250G
  • Price₹48000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number128422
  • Product descriptionmono-Ethyl fumarate 95%
  • Packaging25G
  • Price₹3658.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number92585
  • Product descriptionmono-Ethyl fumarate certified reference material, TraceCERT?
  • Packaging50MG
  • Price₹6614.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0359 Monoethyl Fumarate min. 97.0 % 25G ₹7600 2022-05-26 Buy
TCI Chemicals (India) F0359 Monoethyl Fumarate min. 97.0 % 250G ₹48000 2022-05-26 Buy
Sigma-Aldrich(India) 128422 mono-Ethyl fumarate 95% 25G ₹3658.85 2022-06-14 Buy
Sigma-Aldrich(India) 92585 mono-Ethyl fumarate certified reference material, TraceCERT? 50MG ₹6614.08 2022-06-14 Buy

Properties

Melting point :66-68 °C (lit.)
Boiling point :147 °C/16 mmHg (lit.)
Density :1.1109
refractive index :1.4500 (estimate)
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Crystalline Powder
pka :3.45±0.10(Predicted)
color :Almost white to beige
Water Solubility :Soluble in water.
BRN :1723588
Dielectric constant :6.5（23.0℃）
CAS DataBase Reference :2459-05-4(CAS DataBase Reference)
NIST Chemistry Reference :Ethyl hydrogen fumarate(2459-05-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Monoethyl fumarate is the Monoethyl ester form of fumarate. It is a kind of effective preservative and polymerization agent for macromolecular material. Monoethyl fumarate is capable of inhibiting the growth of bacteria, yeast and mold and prolonging the storage time of feed can. It can also be used for long-term systemic therapy in the treatment of psoriasis (a chronic hyperproliferative inflammatory skin disorder). It is the most active ingredient in the antipsoriasis drug Fumadem. The mechanism is likely to be related to its effect of improvement of keratinocyte differentiation and inhibition of keratinocyte proliferation. Monomethyl fumarate has beneficial effects on the inflamed blood–brain barrier. It increases levels of endogenous antioxidant proteins in brain endothelial cells and reduces expression of VCAM-1 in inflamed brain endothelial cells. Transendothelial monocyte migration is limited upon MMF treatment.

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Related product price

Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
Monoethyl fumarate
₹0.00 /25KG
Monoethyl fumarate CAS:2459-05-4
Hebei Yanxi Chemical Co., Ltd.
Monoethyl fumarate
₹10.00 /100kg
Monoethyl fumarate CAS:2459-05-4
Hebei Guanlang Biotechnology Co,.LTD
Monoethyl Fumarate
₹2.00 /50KG
Monoethyl Fumarate CAS:2459-05-4
CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd. Alfa Aesar Triveni chemicals Pharmaffiliates Analytics and Synthetics P. Ltd Refsyn Biosciences Pvt., Ltd.