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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cytoskeletal Signaling >Microtubule Associated inhibitors >NOCODAZOLE

NOCODAZOLE

NOCODAZOLE Structure
  • ₹3723.8 - ₹49026.43
  • Product name: NOCODAZOLE
  • CAS: 31430-18-9
  • MF: C14H11N3O3S
  • MW: 301.32
  • EINECS:250-626-5
  • MDL Number:MFCD00005588
  • Synonyms:[5-(2-THIENYLCARBONYL)-1H-BENZIMIDAZOL-2-YL]CARBONIC ACID, METHYL ESTER;METHYL[5-(2-THIENYLCARBONYL)-1H-BENZIMADAZOL-2-YL]CARBAMATE;METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMIDAZOL-2-YL)CARBAMATE;METHYL [5-(2-THIENYLCARBONYL)-1H-BENZ-IMIDAZOLE-2-YL]-CARBAMATE;METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMODAZOL-2YL)-CARBAMATE;METHYL N-(5-THENOYL-2-BENZIMIDAZOLYL)CARBAMATE;Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate, Oncodazole, R 17934, [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester, Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate;N-[6-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbamic Acid Methyl Ester
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 2MG
  • 10MG
  • 25MG
  • 50MG
  • 100MG
  • 1ML
  • ManufacturerTCI Chemicals (India)
  • Product numberN1138
  • Product descriptionNocodazole
  • Packaging25MG
  • Price₹11000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberN1138
  • Product descriptionNocodazole
  • Packaging100MG
  • Price₹31200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1404
  • Product descriptionNocodazole ≥99% (TLC), powder
  • Packaging50MG
  • Price₹49026.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1404
  • Product descriptionNocodazole ≥99% (TLC), powder
  • Packaging10MG
  • Price₹12286.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number487928
  • Product descriptionNocodazole - CAS 31430-18-9 - Calbiochem Inhibitor of mitosis.
  • Packaging10MG
  • Price₹10160
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1665
  • Product descriptionNocodazole Ready Made Solution 5?mg/mL, DMSO solution
  • Packaging1ML
  • Price₹8166.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1404
  • Product descriptionNocodazole ≥99% (TLC), powder
  • Packaging2MG
  • Price₹3723.8
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N1138 Nocodazole 25MG ₹11000 2022-05-26 Buy
TCI Chemicals (India) N1138 Nocodazole 100MG ₹31200 2022-05-26 Buy
Sigma-Aldrich(India) M1404 Nocodazole ≥99% (TLC), powder 50MG ₹49026.43 2022-06-14 Buy
Sigma-Aldrich(India) M1404 Nocodazole ≥99% (TLC), powder 10MG ₹12286.38 2022-06-14 Buy
Sigma-Aldrich(India) 487928 Nocodazole - CAS 31430-18-9 - Calbiochem Inhibitor of mitosis. 10MG ₹10160 2022-06-14 Buy
Sigma-Aldrich(India) SML1665 Nocodazole Ready Made Solution 5?mg/mL, DMSO solution 1ML ₹8166.2 2022-06-14 Buy
Sigma-Aldrich(India) M1404 Nocodazole ≥99% (TLC), powder 2MG ₹3723.8 2022-06-14 Buy

Properties

Melting point :300 °C (dec.)
Density :1.490
refractive index :1.6740 (estimate)
storage temp. :-20°C
solubility :DMSO: 10 mg/mL, soluble
form :powder
pka :10.67±0.10(Predicted)
color :white
BRN :1085978
Stability :Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :KYRVNWMVYQXFEU-UHFFFAOYSA-N
CAS DataBase Reference :31430-18-9(CAS DataBase Reference)
EPA Substance Registry System :Nocodazole (31430-18-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Nocodazole reversibly binds tubulin and alters tubulin-associated GTP hydrolysis as well as microtubule dynamics. While nocodazole is used to study many aspects on microtubule function, it is most commonly used to synchronize cell cycling in culture. Typically, nanomolar concentrations of nocodazole reduce both microtubule elongation and shortening velocities, resulting in arrest of cycling in a G2/M phase. Nocodazole is also used to induce the formation of Golgi ministacks in eukaryotic cells.

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