ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cytoskeletal Signaling >Microtubule Associated inhibitors >NOCODAZOLE
NOCODAZOLE
- CAS No.
- 31430-18-9
- Chemical Name:
- NOCODAZOLE
- Synonyms
- R 17934;CS-2010;nsc238159;NOCODAZOLE;NSC 238159;Oncodazole;Norcodazole;Nocodazole,98%;Nocodazole,99+%;Nocodazole (R17934)
- CBNumber:
- CB3239975
- Molecular Formula:
- C14H11N3O3S
- Molecular Weight:
- 301.32
- MOL File:
- 31430-18-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 300 °C (dec.) |
|---|---|
| Density | 1.490 |
| refractive index | 1.6740 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: 10 mg/mL, soluble |
| form | powder |
| pka | 10.67±0.10(Predicted) |
| color | white |
| BRN | 1085978 |
| Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months. |
| InChIKey | KYRVNWMVYQXFEU-UHFFFAOYSA-N |
| CAS DataBase Reference | 31430-18-9(CAS DataBase Reference) |
| EPA Substance Registry System | Nocodazole (31430-18-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H341-H361d | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | T,C,F,Xn | |||||||||
| Risk Statements | 61-40-36/37/38-34-11-68-63 | |||||||||
| Safety Statements | 53-45-36/37/39-26-16-36/37 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DD6521000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29349990 | |||||||||
| Toxicity | sln-smc 1 ppm/16H MUREAV 141,15,84 | |||||||||
| NFPA 704 |
|
NOCODAZOLE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M1404 | Nocodazole ≥99% (TLC), powder | 31430-18-9 | 2MG | ₹3723.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1665 | Nocodazole Ready Made Solution 5?mg/mL, DMSO solution | 31430-18-9 | 1ML | ₹8166.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M1404 | Nocodazole ≥99% (TLC), powder | 31430-18-9 | 10MG | ₹12286.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M1404 | Nocodazole ≥99% (TLC), powder | 31430-18-9 | 50MG | ₹49026.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 487928 | Nocodazole - CAS 31430-18-9 - Calbiochem Inhibitor of mitosis. | 31430-18-9 | 10MG | ₹10160 | 2022-06-14 | Buy |
NOCODAZOLE Chemical Properties,Uses,Production
Description
Nocodazole reversibly binds tubulin and alters tubulin-
Chemical Properties
Amber Powder
Uses
Nocodazole has been shown to enhance CRISPR genome editing efficiency. To see other small molecule CRISPR enhancers, visit sigma.com/CRISPR-enhancers.
Definition
ChEBI: A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.
General Description
White powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
NOCODAZOLE may be sensitive to heat. .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition NOCODAZOLE emits toxic fumes of sulfur oxides and nitrogen oxides.
Fire Hazard
Flash point data for NOCODAZOLE are not available; however, NOCODAZOLE is probably combustible.
Biological Activity
Microtubule inhibitor; inhibits mitosis.
Safety Profile
Poison by intraperitoneal route.An experimental teratogen. Other experimentalreproductive effects. Human mutation data reported.When heated to decomposition it emits toxic fumes ofSOx and NOx. See also CARBAMATES
NOCODAZOLE Preparation Products And Raw materials
Raw materials
chevron_left
1of5
chevron_rightPreparation Products
Global( 214)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26368 | 58 | Inquiry |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9626 | 58 | Inquiry |
31430-18-9(NOCODAZOLE)Related Search:
chevron_left
1of4
chevron_right
[5-(2-THIENYLCARBONYL)-1H-BENZIMIDAZOL-2-YL]CARBONIC ACID, METHYL ESTER
METHYL[5-(2-THIENYLCARBONYL)-1H-BENZIMADAZOL-2-YL]CARBAMATE
METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMIDAZOL-2-YL)CARBAMATE
METHYL [5-(2-THIENYLCARBONYL)-1H-BENZ-IMIDAZOLE-2-YL]-CARBAMATE
METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMODAZOL-2YL)-CARBAMATE
METHYL N-(5-THENOYL-2-BENZIMIDAZOLYL)CARBAMATE
Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate, Oncodazole, R 17934, [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester, Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
N-[6-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbamic Acid Methyl Ester
NOCODAZOLE
R 17934
n-(5-(2-thienoyl)-2-benzimidazolyl)carbamicacidmethylester
NSC 238159
nsc238159
Oncodazole
METHYL-(5-(2-THIENYLCARBONYL)-1H-*BENZIM IDAZOL-2-YL
Methyl (5-(thiophene-2-carbonyl)-1H-benzo[d]iMidazol-2-yl)carbaMate
methyl 6-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-ylcarbamate
5-(2-Thenoyl)-1H-benzimidazole-2-carbamic acid methyl ester
Nocodazole,98%
Nocodazole,99+%
Methyl [5-(2-thienylcarbonyl)-1h-benz-imidazole-2-yl]-carbamat
Nocodazole,Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate, Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate, Oncodazole, R 17934, [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid
Nocodazole, 98% 50MG
(5-(2-thienylcarbonyl)-1h-benzimidazol-2-yl)-carbamicacimethylester
[[5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]]carbamic acid methyl ester
[6-(Thiophene-2-carbonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester
2-Benzimidazolecarbamic acid, 5-(2-thenoyl)-, methyl ester
2-Benzimidazolecarbamic acid, 5-(2-thienoyl)-, methyl ester
2-Benzimidazolecarbamic acid, 5-(2-thienylcarbonyl)-, methyl ester
5-(2-thenoyl)-2-benzimidazolecarbamicacimethylester
5-(2-thienoyl)-2-benzimidazolecarbamicacimethylester
5-(2-thienylcarbonyl)-2-benzimidazolecarbamicacimethylester
Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazole-2-yl)-, methyl ester
Carbamic acid, [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester
Carbamic acid, N-[5-(2-thenoyl)-1H-benzimidazol-2-yl]-, methyl ester
Methyl 5-(2-thenoyl)-2-benzimidazolecarbamate
Methyl 5-(2-thienoyl)-2-benzimidazolecarbamate
methyl5-(2-thenoyl)-2-benzimidazolecarbamate
N-(5-(2-Thenoyl)-2-benzimidazolyl)carbamic acid methyl ester
N-(5-(2-Thienoyl)-2-benzimidazolyl)carbamic acid methyl ester
InSolution? Nocodazole
Nocodazole solution (5 mg/ml in DMSO)
NOCODAZOLE USP/EP/BP
Carbamic acid, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-, methyl ester
Nocodazole Nocodazole
Nocodazole (Oncodazole)
methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
CS-2010
Nocodazole - CAS 31430-18-9 - Calbiochem
InSolution Nocodazole - CAS 31430-18-9 - Calbiochem
Norcodazole
Nocodazole (R17934)
31430-18-9
313430-18-9
C14H11N3O3S
Cytoskeleton and Extracellular Matrix
Heterocyclic Building Blocks
Microtobule Inhibitors