Welcome to chemicalbook!
China english Japan Germany India
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
head sculpture My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >protein tyrosine kinase >NVP-BHG712

NVP-BHG712

NVP-BHG712 Structure
  • ₹5500 - ₹64224.6
  • Product name: NVP-BHG712
  • CAS: 940310-85-0
  • MF: C26H20F3N7O
  • MW: 503.48
  • EINECS:
  • MDL Number:MFCD20272929
  • Synonyms:NVP-BHG712;4-Methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]benzamide;4-methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide;NVP-BHG712 4-Methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]benzamide;4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluorome;NVP-BHG 712; NVP BHG 712;CS-475;CS-688
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberN1099
  • Product descriptionNVP-BHG 712
  • Packaging10MG
  • Price₹5500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberN1099
  • Product descriptionNVP-BHG 712
  • Packaging50MG
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0333
  • Product descriptionNVP-BHG712 ≥98% (HPLC)
  • Packaging5MG
  • Price₹15939.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0333
  • Product descriptionNVP-BHG712 ≥98% (HPLC)
  • Packaging25MG
  • Price₹64224.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N1099 NVP-BHG 712 10MG ₹5500 2022-05-26 Buy
TCI Chemicals (India) N1099 NVP-BHG 712 50MG ₹14800 2022-05-26 Buy
Sigma-Aldrich(India) SML0333 NVP-BHG712 ≥98% (HPLC) 5MG ₹15939.6 2022-06-14 Buy
Sigma-Aldrich(India) SML0333 NVP-BHG712 ≥98% (HPLC) 25MG ₹64224.6 2022-06-14 Buy

Properties

Density :1.41
storage temp. :-20°C
solubility :DMSO: >15mg/mL
form :powder
pka :13.20±0.70(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

The EphB4 receptor tyrosine kinase (cloned from erythropoietin-producing hepatocellular carcinoma) and its ligand ephrinB2 play an important role in embryonic vessel development and vascular remodeling. Signaling from this pair is also involved in tumor angiogenesis. NVP-BHG712 is an orally bioavailable inhibitor of EphB4 kinase autophosphorylation (ED50 = 25 nM). It is selective for EphB4, demonstrating an ED50 value of 4.2 μM at the related VEGFR2 receptor and ED50 values >10 μM against a panel of 40 additional kinases. At 3-30 mg/kg, NVP-BHG712 dose dependently inhibits VEGF-directed vessel formation in an in vivo mouse model of angiogenesis.

More related product prices

AT9283 KX2-391 Crenolanib N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea Nintedanib 872511-34-7 NVP-BAW2881

Suppliers and manufacturers

TCI Chemicals (India) Pvt. Ltd.
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
Career Henan Chemica Co
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.