OXYPHENYL BUTAZONE
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- ₹13996.73 - ₹54806.98
- Product name: OXYPHENYL BUTAZONE
- CAS: 129-20-4
- MF: C19H20N2O3
- MW: 324.37
- EINECS:204-936-2
- MDL Number:MFCD00057278
- Synonyms:butanora ;Butanova;Butapirone;Butazonic;Californit;Crovaril;Deflogin;Etrozolidina
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0540
- Product descriptionOxyphenbutazone ≥98% (HPLC)
- Packaging10MG
- Price₹13996.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0540
- Product descriptionOxyphenbutazone ≥98% (HPLC)
- Packaging50MG
- Price₹54806.98
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0540 | Oxyphenbutazone ≥98% (HPLC) | 10MG | ₹13996.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0540 | Oxyphenbutazone ≥98% (HPLC) | 50MG | ₹54806.98 | 2022-06-14 | Buy |
Properties
Melting point :109-111°C
Boiling point :462.71°C (rough estimate)
Density :1.2118 (rough estimate)
refractive index :1.6140 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
pka :pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
form :powder
color :white to brown
Water Solubility :20mg/L(room temperature)
Stability :Hygroscopic
CAS DataBase Reference :129-20-4(CAS DataBase Reference)
IARC :3 (Vol. 13, Sup 7) 1987
EPA Substance Registry System :3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl- (129-20-4)
Boiling point :462.71°C (rough estimate)
Density :1.2118 (rough estimate)
refractive index :1.6140 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
pka :pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
form :powder
color :white to brown
Water Solubility :20mg/L(room temperature)
Stability :Hygroscopic
CAS DataBase Reference :129-20-4(CAS DataBase Reference)
IARC :3 (Vol. 13, Sup 7) 1987
EPA Substance Registry System :3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl- (129-20-4)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Oxyphenbutazone is a metabolite of phenylbutazone . Both compounds were identified as having anti-inflammatory effects in early studies, and, as a result, are considered NSAIDs. Interestingly, the effects of the two compounds in animal models differ, with phenylbutazone having anti-inflammatory effects in rheumatic diseases and oxyphenbutazone reducing edema in certain types of acute inflammation. Oxyphenbutazone is a poor inhibitor of prostaglandin synthesis, but, like other NSAIDs, it inhibits organic anion transporter 1 (Ki = 32 μM). It inhibits the growth of MH60/BSF-2 cells induced by IL-6 (IC50 = 7.5 μM). Oxyphenbutazone stimulates neurite outgrowth at 1.5 μM and sensitizes M. tuberculosis to antimicrobials.Related product price
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