Parthenolide
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- ₹3900 - ₹21195.35
- Product name: Parthenolide
- CAS: 20554-84-1
- MF: C15H20O3
- MW: 248.32
- EINECS:692-532-0
- MDL Number:MFCD00134592
- Synonyms:[1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;(1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic acid γ-lactone;4,5alpha-epoxy-6beta-hydroxy-germacra-1(10),11(13)-dien-12-oic acid gamma-lactone;Germacra-1(10),11(13)-dien-12-oic acid, 4,5-alpha-epoxy-6-beta-hydroxy-, gamma-lactone;Parthenolide;Parthenolide ((-)-Parthenolide);PartheNAlide
5 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 50MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberP1982
- Product descriptionParthenolide
- Packaging25MG
- Price₹3900
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberP1982
- Product descriptionParthenolide
- Packaging100MG
- Price₹10200
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0667
- Product descriptionParthenolide ≥98% (HPLC)
- Packaging5MG
- Price₹5466.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number512732
- Product descriptionParthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem A cell-permeable sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties.
- Packaging50MG
- Price₹11880.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0667
- Product descriptionParthenolide ≥98% (HPLC)
- Packaging25MG
- Price₹21195.35
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | P1982 | Parthenolide | 25MG | ₹3900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P1982 | Parthenolide | 100MG | ₹10200 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | P0667 | Parthenolide ≥98% (HPLC) | 5MG | ₹5466.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 512732 | Parthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem A cell-permeable sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties. | 50MG | ₹11880.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0667 | Parthenolide ≥98% (HPLC) | 25MG | ₹21195.35 | 2022-06-14 | Buy |
Properties
Melting point :115-116 °C (lit.)
alpha :D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)
Boiling point :394.1±42.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml)
form :White solid
color :White
Merck :14,7048
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1
InChIKey :KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES :O1C(=O)C(=C)[C@]2([H])CCC(C)=CCC[C@@]3(C)O[C@]3([H])[C@@]12[H] |t:10|
LogP :2.424 (est)
CAS DataBase Reference :20554-84-1
alpha :D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)
Boiling point :394.1±42.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml)
form :White solid
color :White
Merck :14,7048
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1
InChIKey :KTEXNACQROZXEV-PVLRGYAZSA-N
SMILES :O1C(=O)C(=C)[C@]2([H])CCC(C)=CCC[C@@]3(C)O[C@]3([H])[C@@]12[H] |t:10|
LogP :2.424 (est)
CAS DataBase Reference :20554-84-1
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium). It inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml). Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription. This compound has also been shown to block inflammation by inhibiting signaling through NF-κB. Inhibition of NF-κB by parthenolide can be achieved by direct binding of the pattern recognition receptor NOD2 by parthenolide.Related product price
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