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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >PERHEXILINE MALEATE SALT

PERHEXILINE MALEATE SALT

PERHEXILINE MALEATE SALT Structure
  • ₹16551.43 - ₹64841.75
  • Product name: PERHEXILINE MALEATE SALT
  • CAS: 6724-53-4
  • MF: C23H39NO4
  • MW: 393.56
  • EINECS:229-775-5
  • MDL Number:MFCD00057329
  • Synonyms:2-(2,2-dicyclohexylethyl)piperidinemaleate ;2-(2,2-dicyclohexylethyl)-piperidinmaleate(1:1) ;perhexilinemaleate ;perhexilene maleate;Pexid;WSM-3978;rac Perhexiline Maleate;2-(2,2-dicyclohexylethyl)piperidinium hydrogen maleate
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0120
  • Product descriptionPerhexiline maleate salt ≥98% (HPLC)
  • Packaging10MG
  • Price₹16551.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0120
  • Product descriptionPerhexiline maleate salt ≥98% (HPLC)
  • Packaging50MG
  • Price₹64841.75
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0120 Perhexiline maleate salt ≥98% (HPLC) 10MG ₹16551.43 2022-06-14 Buy
Sigma-Aldrich(India) SML0120 Perhexiline maleate salt ≥98% (HPLC) 50MG ₹64841.75 2022-06-14 Buy

Properties

Melting point :181-183°C
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :powder
color :white to tan

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Perhexiline is a carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor that was originally developed as an anti-anginal drug in the 1970s. It inhibits rat heart and liver CPT1 (IC50 = 77 and 148 μM, respectively) and rat heart CPT2 (IC50 = 79 μM). Inhibition of CPT reduces uptake of long-chain fatty acids into the mitochondria, thereby shifting cellular metabolism from β-oxidation to glycolysis. Perhexilin inhibits mTORC1 signaling at 10 μM and induces autophagy ~7-fold at a concentration of 10 μM in MCF-7 cells.

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