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PHORBOL 12,13-DIBUTYRATE

PHORBOL 12,13-DIBUTYRATE Structure
  • ₹10500 - ₹64365.45
  • Product name: PHORBOL 12,13-DIBUTYRATE
  • CAS: 37558-16-0
  • MF: C28H40O8
  • MW: 504.61
  • EINECS:
  • MDL Number:MFCD00036783
  • Synonyms:butanoicacid,1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymet ;hyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diy ;lester,(1ar-(1a-alpha,1b-beta,4a-beta,7a-alpha,7b-alpha,8-alpha,9-beta,9a-al ;PDBU;PHORBOL 12,13-DIBUTYRATE;PHORBOL 12,13-DIBUTYRATE, 4BETA;(1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-4aβ,7bα-dihydroxy-3-hydroxymethyl-1,1,6,8α-tetramethyl-5-oxo-5H-cyclopropa[3,4]benz[1,2-e]azulene-9β,9aα-diol 9,9a-dibutyrate;9β,9aα-Bis(butyryloxy)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα-dihydroxy-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one
Price5 Properties Safety Information Description
5 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product number524390
  • Product descriptionPhorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem Strong irritant for mouse skin, but only moderately active as a tumor promoter.
  • Packaging1MG
  • Price₹10500
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1269
  • Product descriptionPhorbol 12,13-dibutyrate ≥98% (TLC), powder
  • Packaging1MG
  • Price₹10835.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number524390
  • Product descriptionPhorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem Strong irritant for mouse skin, but only moderately active as a tumor promoter.
  • Packaging5MG
  • Price₹26250
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1269
  • Product descriptionPhorbol 12,13-dibutyrate ≥98% (TLC), powder
  • Packaging5MG
  • Price₹28318.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1269
  • Product descriptionPhorbol 12,13-dibutyrate ≥98% (TLC), powder
  • Packaging10MG
  • Price₹64365.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 524390 Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem Strong irritant for mouse skin, but only moderately active as a tumor promoter. 1MG ₹10500 2022-06-14 Buy
Sigma-Aldrich(India) P1269 Phorbol 12,13-dibutyrate ≥98% (TLC), powder 1MG ₹10835.83 2022-06-14 Buy
Sigma-Aldrich(India) 524390 Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem Strong irritant for mouse skin, but only moderately active as a tumor promoter. 5MG ₹26250 2022-06-14 Buy
Sigma-Aldrich(India) P1269 Phorbol 12,13-dibutyrate ≥98% (TLC), powder 5MG ₹28318.2 2022-06-14 Buy
Sigma-Aldrich(India) P1269 Phorbol 12,13-dibutyrate ≥98% (TLC), powder 10MG ₹64365.45 2022-06-14 Buy

Properties

Boiling point :513.95°C (rough estimate)
Density :1.1270 (rough estimate)
refractive index :1.4480 (estimate)
storage temp. :-20°C
solubility :H2O: 30 μM
pka :11.15±0.70(Predicted)
form :powder
color :clear, light yellow, film
Water Solubility :H2O: 30μM
DMSO: soluble
acetone: soluble
ethanol: soluble BRN :6551234
CAS DataBase Reference :37558-16-0(CAS DataBase Reference)
EPA Substance Registry System :Phorbol 12,13-dibutyrate (37558-16-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phorbol-12,13-dibutyrate is a strong irritant for mouse skin, but only moderately active as a tumor promoter. This compound activates protein kinase C. Phorbol-12,13-dibutyrate stimulates the phosphorylation of Na+,K+- ATPase, thereby inhibiting its activity. Promotes the expression of inducible NOS in cultured hepatocytes. Phorbol-12,13-dibutyrate is commonly used in binding studies or in applications requiring high concentrations of phorbol compounds.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Phorbol 12,13-dibutyrate
₹56.00 /1mg
Phorbol 12,13-dibutyrate CAS:37558-16-0
Career Henan Chemica Co
PHORBOL 12,13-DIBUTYRATE
₹0.37 /1KG
PHORBOL 12,13-DIBUTYRATE CAS:37558-16-0
InvivoChem
LEAPCHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
SHANGHAI KEAN TECHNOLOGY CO., LTD.
DAYANG CHEM (HANGZHOU) CO.,LTD Merck Millipore Biosynth Biological Technology (Suzhou) Co Ltd