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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Idiopathic pulmonary fibrosis(IPF) >Pirfenidone

Pirfenidone

Pirfenidone Structure
  • ₹8100 - ₹47402.68
  • Product name: Pirfenidone
  • CAS: 53179-13-8
  • MF: C12H11NO
  • MW: 185.22
  • EINECS:621-260-7
  • MDL Number:MFCD00866047
  • Synonyms:S-7701;5-methyl-1-phenyl-2-pyridone;5-methyl-1-phenyl-pyridin-2-one;5-methyl-1-phenylpyridin-2-one;Pirfenidone, >=99%;Pirfenidone(S-7701,AMR-69);2(1H)-Pyridinone,5-Methyl-1-phenyl-;Pirfenidone ( 5-Methyl-1-Phenyl-2(1H)-Pyridinone)
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1871
  • Product descriptionPirfenidone min. 98.0 %
  • Packaging100MG
  • Price₹8100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1871
  • Product descriptionPirfenidone min. 98.0 %
  • Packaging1G
  • Price₹20800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2116
  • Product descriptionPirfenidone ≥97% (HPLC)
  • Packaging10MG
  • Price₹11983.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2116
  • Product descriptionPirfenidone ≥97% (HPLC)
  • Packaging50MG
  • Price₹47402.68
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1871 Pirfenidone min. 98.0 % 100MG ₹8100 2022-05-26 Buy
TCI Chemicals (India) P1871 Pirfenidone min. 98.0 % 1G ₹20800 2022-05-26 Buy
Sigma-Aldrich(India) P2116 Pirfenidone ≥97% (HPLC) 10MG ₹11983.28 2022-06-14 Buy
Sigma-Aldrich(India) P2116 Pirfenidone ≥97% (HPLC) 50MG ₹47402.68 2022-06-14 Buy

Properties

Melting point :96-97°C
Boiling point :329.1±15.0 °C(Predicted)
Density :1.137±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: ≥10 mg/mL, soluble
form :solid
pka :-0.16±0.63(Predicted)
color :Off-white
Water Solubility :Soluble to 20 mM in water
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey :ISWRGOKTTBVCFA-UHFFFAOYSA-N
SMILES :C1(=O)N(C2=CC=CC=C2)C=C(C)C=C1
CAS DataBase Reference :53179-13-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Fibrogenesis, as occurs in wound healing and fibrotic diseases, involves oxidative stress and inflammation followed by fibrosis. Pirfenidone is an orally active small molecule drug with antioxidant, anti-inflammatory, and anti-fibrotic effects. It has numerous cellular and in vivo effects, including the reduction of inflammatory cytokine production, suppression of TGF-β expression and TGF-mediated collagen I expression, and diminution of markers of oxidative stress. Pirfenidone has demonstrated effectiveness in both animal and human idiopathic pulmonary fibrosis. Moreover, it has use in other conditions with a significant fibrotic component, including tissue scarring, liver fibrosis, and diabetic nephropathy.

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