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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Endocrinology & Hormones >Estrogen / progestogen Receptor Antagonists >Raloxifene hydrochloride

Raloxifene hydrochloride

Raloxifene hydrochloride Structure
  • ₹15144.18 - ₹99535.88
  • Product name: Raloxifene hydrochloride
  • CAS: 82640-04-8
  • MF: C28H28ClNO4S
  • MW: 510.04
  • EINECS:639-789-7
  • MDL Number:MFCD01938233
  • Synonyms:RALOXIFENE HCL;Raloxifene hydrochloride,Keoxifene hydrochloride, LY 156758, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride;Raloxifene Hydrochloride (200 mg);2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride;(6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)Methanone hydrochloride;Evista(Raloxifene Hydrochloride;(6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)-(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanon;[6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone,hydrochloride (1:1)
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1852
  • Product descriptionRaloxifene Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹15144.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR1402
  • Product descriptionRaloxifene hydrochloride solid
  • Packaging500MG
  • Price₹53432.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR1402
  • Product descriptionRaloxifene hydrochloride solid
  • Packaging1G
  • Price₹99535.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1852 Raloxifene Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹15144.18 2022-06-14 Buy
Sigma-Aldrich(India) R1402 Raloxifene hydrochloride solid 500MG ₹53432.2 2022-06-14 Buy
Sigma-Aldrich(India) R1402 Raloxifene hydrochloride solid 1G ₹99535.88 2022-06-14 Buy

Properties

Melting point :250-253°C
storage temp. :2-8°C
solubility :DMSO: 28 mg/mL, soluble
form :solid
color :light yellow
λmax :286nm(lit.)
Merck :14,8098
BCS Class :2
InChIKey :BKXVVCILCIUCLG-UHFFFAOYSA-N
SMILES :C1(C(=O)C2C=CC(OCCN3CCCCC3)=CC=2)C2C=CC(O)=CC=2SC=1C1C=CC(O)=CC=1.Cl
CAS DataBase Reference :82640-04-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM), binding to ERα and ERβ. Tissue-dependently blocks or activates estrogen-induced transcription. Exhibits estrogen agonist behavior in bone but acts as an anti-estrogen in breast and uterine tissue. Raloxifene hydrochloride exhibits inhibitory effects of progesterone receptor induction by estrogen in D12 rat hypothalamic cells. Raloxifene hydrochloride is a substrate of Estrogen Receptor.

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