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ChemicalBook > Product Catalogue >Natural Products >Alkaloids >Seneciphylline

Seneciphylline

Seneciphylline Structure
  • ₹52079.08
  • Product name: Seneciphylline
  • CAS: 480-81-9
  • MF: C18H23NO5
  • MW: 333.38
  • EINECS:
  • MDL Number:MFCD00221722
  • Synonyms:ALPHA-LONGILOBINE;SENECIPHYLLIN;(15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione;13,19-didehydro-12-hydroxysenecionan-11,16-dione ;16-dione,13,19-didehydro-12-hydroxy-senecionan-1 ;16-dione,13,19-didehydro-12-hydroxy-senecionin-1 ;NSC 30622;oxy-6-methyl-5-methylene(1,6)dioxacyclodode///
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number73913
  • Product descriptionSeneciphylline analytical standard
  • Packaging5MG
  • Price₹52079.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 73913 Seneciphylline analytical standard 5MG ₹52079.08 2022-06-14 Buy

Properties

Melting point :217°C
alpha :D -128° (chloroform)
Boiling point :470.34°C (rough estimate)
Density :1.2467 (rough estimate)
refractive index :1.5740 (estimate)
storage temp. :-20°C
solubility :DMF: 5 mg/ml; DMSO: 2 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form :Solid
pka :12.43±0.20(Predicted)
color :White to off-white
Stability :Stable, but reacts with oxygen in the air. Incompatible with alkali, oxidizing agents. Store under inert gas.
LogP :0.810 (est)
CAS DataBase Reference :480-81-9
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Seneciphylline (480-81-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Seneciphylline, a pyrrolizidine alkaloid, one of the main components of Chinese medicine herb Tusanqi, which is a reason of the hepatic sinusoidal obstruction syndrome (HSOS). In addition, experiments on rats have shown that seneciphylline had adverse effects on the development and organic morphodifferentiation of embryos, thus the pregnant people exposed to Hebra may get potential risk on the fetus.

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