Vatalanib Dihydrochloride
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- ₹6689.85 - ₹22526.83
- Product name: Vatalanib Dihydrochloride
- CAS: 212141-51-0
- MF: C20H17Cl3N4
- MW: 419.74
- EINECS:
- MDL Number:MFCD08458964
- Synonyms:CGP-79787 Dihydrochlorid;N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Dihydrochloride;Vatalanib Dihydrochloride;CGP-79787 Dihydrochloride;Vatalanib 2hcl((ZK-222584,PTK 787);Vatalanib dihydrochloride (PTK787);CGP-79787;CGP-79787D
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML2498
- Product descriptionVatalanib dihydrochloride ≥98% (HPLC)
- Packaging50MG
- Price₹22526.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2498
- Product descriptionVatalanib dihydrochloride ≥98% (HPLC)
- Packaging10MG
- Price₹6689.85
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML2498 | Vatalanib dihydrochloride ≥98% (HPLC) | 50MG | ₹22526.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML2498 | Vatalanib dihydrochloride ≥98% (HPLC) | 10MG | ₹6689.85 | 2022-06-14 | Buy |
Properties
Melting point :268-2700C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :212141-51-0
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml with warming) or in Water (up to 100 mg/ml)
form :solid
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :212141-51-0
Safety Information
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Description
Vatalanib is an antagonist of the VEGF receptors, inhibiting the receptor tyrosine kinase activities of VEGFR1 (Flt1), VEGFR2 (KDR), and VEGFR3 (Flt4) with IC50 values of 77, 37, and 190 nM, respectively. It less potently inhibits PDGF and c-Kit (IC50 = 600 and 700 nM) and has no effect on a large panel of additional kinases. Vatalanib completely blocks retinal neovascularization in oxygen-induced ischemic retinopathy in mice, suggesting its use in diabetic retinopathy and other diseases featuring aberrant vascular development.Related product price
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